Effect of Peer-led Educational Intervention on Treatment Outcomes Among Adults With Drug-susceptible Pulmonary Tuberculosis in South Omo and Ari Zone, Southern Ethiopia

NCT07387601 | Recruiting

• 1 other identifier: 4064/2024
• Study Type: interventional
• Target: 250
• Locations: 1 country
• Sites: 1

Brief Summary

The study might come up with valuable findings to address poor treatment outcome, poor quality of life, disability score and depressive symptoms. The findings may also be decreased health professional workload. The findings would be supportive evidences for policy makers, program managers, to clinician as well as the patients themselves and for other researchers. The study may help to promote and maintain good treatment outcome for the patients in the study area as well as the country. The findings will also be used for teaching \& learning purposes in educational \& training programs.

Conditions

to Assess Effect of Peer-led Education

Keywords

Southern Ethiopia south omo

Outcome Measures

Primary Outcomes (1)

• treatment success rate

  as defined by 7th edition of Ethiopian guidelines for clinical and programmatic management of TB, TB/HIV, DR-TB and Leprosy and by WHO. Data on the patients' status on the primary outcome variable will be extracted from TB register logbook.

  the primary outcome will be measured at the end of 6 months i.e after July 24/2026

Study Arms (1)

Peer-Led Educational Intervention plus Standard TB Treatment

ACTIVE COMPARATOR

Participants in this arm received a structured peer-led educational intervention in addition to standard anti-tuberculosis therapy for drug-susceptible pulmonary tuberculosis. The intervention consisted of education and support sessions delivered by trained peer educators who were previously treated and successfully cured of drug-susceptible pulmonary TB. The sessions focused on improving treatment adherence, enhancing knowledge about tuberculosis and its transmission, managing medication side effects, reducing stigma, and promoting healthy behaviors during treatment. The peer-led sessions were conducted \[weekly/biweekly/monthly - specify\] over the course of the standard TB treatment period (typically 6 months), using interactive methods such as group discussions, experience sharing, question-and-answer sessions, and motivational support. Educational materials were provided to reinforce key messages

Combination Product: peer-led education

Interventions

peer-led education COMBINATION_PRODUCT

The Intervention is a structured, evidence-based program designed to promote positive and sustained behavioral changes among participants through education, counseling, and supportive follow-up

Peer-Led Educational Intervention plus Standard TB Treatment

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adults with new drug-susceptible pulmonary TB who will be diagnosed in bacteriological diagnostic methods
• not participating in similar study,
• mentally capable to provide consent,
• physically capable of following the intervention.

You may not qualify if:

• Seriously ill patients at the time of screening or enrollment
• Tuberculosis patients with a known plan to be transferred out of the study sites

Sponsors & Collaborators

• Bahirdar University: lead

Study Sites (1)

Jinka University

Jinka, Southern Ethiopia, Ethiopia

RECRUITING

Related Publications (1)

• Authors (full names or at least last name + initials, in order) Article title Journal name Publication date (year, and month if available) Volume number Page numbers

  RESULT

Central Study Contacts

Moges Getie Workie, MPH in Epidemiology

CONTACT

+251949998832/918059106; getiemoges@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: NETWORK
• Responsible Party: SPONSOR

Model Details: This is a cluster randomized controlled trial with a parallel assignment design to evaluate the effect of a peer-led educational intervention on treatment outcomes, quality of life, disability, and depression among adult tuberculosis patients

Study Record Dates

• First Submitted: January 28, 2026
• First Posted: February 4, 2026
• Study Start: February 19, 2026
• Primary Completion: July 12, 2026
• Study Completion: July 22, 2026
• Last Updated: July 6, 2026

Record last verified: 2026-02

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL
• Time Frame: February 10/2026-July 24/2026
• Access Criteria: up on the request the correspondence author

Locations

ET (1)