Knee Joint Position Sense in Knee Osteoarthritis

NCT07386977 | Active Not Recruiting

• 1 other identifier: LHU-FTR-ZSBD-04
• Study Type: observational
• Target: 88
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study was to compare knee joint position sense between sitting with visual input and prone without visual input in individuals with and without knee osteoarthritis.

Conditions

Knee Osteoarthritis; Gonarthrosis

Keywords

knee osteoarthritis; proprioception; angular error; joint position sense; gonarthrosis

Outcome Measures

Primary Outcomes (1)

• Proprioception Measurement

  During the measurement, the inclinometer was positioned over the proximal one-third of the fibula, with its axis aligned with the knee joint line, and secured using a strap. Measurements were performed in both the prone and sitting positions. Participants were instructed to actively move their knee from 90° of flexion toward the target position of 30° of flexion. Upon reaching the perceived target position, participants maintained the position for 5 seconds before returning to the starting position.

  Each measurement was repeated three times, with a 1-minute rest interval between trials. A 2-minute rest period was provided between the two testing positions to allow participants to change position and rest.

Study Arms (2)

Knee Osteoarthritis Group

Participants diagnosed with knee osteoarthritis.

2-True Control Group

Participants without a diagnosis of knee osteoarthritis.

Eligibility Criteria

• Age: 40 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Participants diagnosed with knee osteoarthritis according to Kellgren-Lawrence grades 1-3 were included in the study.

You may qualify if:

• Age between 40 and 80 years,
• A confirmed diagnosis of knee osteoarthritis,
• Absence of any health condition that could interfere with the measurement procedures.

You may not qualify if:

• Refusal to participate in the study,
• Presence of a diagnosed neurological disorder that could affect the measurements,
• Presence of cardiopulmonary instability that could influence the measurements,
• History of knee-related trauma within the past year,
• Receipt of physiotherapy or rehabilitation treatment within the past year,
• History of knee-related surgery,
• Inability to follow verbal instructions due to insufficient cognitive function.

Sponsors & Collaborators

• Lokman Hekim University: lead

Study Sites (1)

Lokman Hekim University

Ankara, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Osteoarthritis, Knee

Condition Hierarchy (Ancestors)

Osteoarthritis; Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases

Study Officials

• ZAHİDE SEDA BAKTIR DOĞAN, Assist. Prof

  Lokman Hekim University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assist. Prof.

Study Record Dates

• First Submitted: January 28, 2026
• First Posted: February 4, 2026
• Study Start: March 1, 2025
• Primary Completion: September 30, 2026
• Study Completion (Estimated): December 30, 2026
• Last Updated: August 21, 2026

Record last verified: 2026-08

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)