Improvement of Sleep Disorders in Patients With Alzheimer's Disease After Sunlight Exposure Therapy.

NCT07386808 | Active Not Recruiting DMC

• 1 other identifier: 202511021RIND
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

This observational study aimed to understand the effect of intervention A on sleep disorders in individuals with Alzheimer's disease receiving sunlight therapy. The primary question of the study was: Does sunlight therapy improve sleep disorders in Alzheimer's disease? Participants will complete a questionnaire, undergo sunlight therapy, and have their sleep patterns recorded for 14 days.

Conditions

Alzheimer's Disease (AD); Sleep Disorders, Circadian Rhythm

Outcome Measures

Primary Outcomes (1)

• Pittsburgh Sleep Quality Index, PSQI

  The Pittsburgh Sleep Quality Index (PSQI) assesses sleep quality. It has seven dimensions: sleep quality, sleep latency, sleep duration, sleep efficiency, sleep disturbance, medication use, and daytime activity impairment. A higher PSQI score indicates poorer sleep quality. The total score ranges from 0 to 21, with a minimum score of 0, indicating very good sleep quality over the past month. Lower scores indicate better sleep quality, while a total score of 5 or below is generally considered to indicate fair sleep quality.

  on enrollment days, 7, and 14 after enrollment

Study Arms (1)

Routine nursing care

OTHER

no additional sunlight therapy

Behavioral: sunlight therapy

Interventions

sunlight therapy BEHAVIORAL

They were informed that sun exposure therapy could effectively improve sleep, and behavioral interventions were discussed to develop a health education plan. Telephone follow-ups were conducted on days 3, 7, 10, and 14 after enrollment to understand the sun exposure practices of the experimental group, including the duration of sun exposure, whether the light source was indoor light or sunlight, and positive encouragement was provided.

Routine nursing care

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Diagnosed with Alzheimer's disease
• CDR: 0.5 - 1 point
• Conscious and able to cooperate with behavioral interventions and telephone interviews
• Complaints of sleep disturbances, including: daytime sleepiness, difficulty falling asleep, fragmented sleep, nighttime awakening, nocturnal wandering, and sunset syndrome.
• A cohabiting family member is required as the primary caregiver, who understands and cooperates with this intervention and has signed a consent form.
• If the patient is already taking sleeping pills, the maintenance dose will not be adjusted.

You may not qualify if:

• Individuals with other brain injury conditions, such as cerebral palsy, brain tumors, traumatic brain injury, or stroke.
• Individuals with visual impairments (assessed by comparing numbers with fingers at a distance of 30 cm upon admission).
• Institutional residents.
• Individuals living alone.
• Individuals unable to cooperate with behavioral interventions and telephone interviews.

Sponsors & Collaborators

• National Taiwan University Hospital: lead

Study Sites (1)

National Taiwan University Hospital

Taipei, Taiwan, 100, Taiwan

Location

MeSH Terms

Conditions

Alzheimer Disease; Sleep Disorders, Circadian Rhythm

Condition Hierarchy (Ancestors)

Dementia; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Tauopathies; Neurodegenerative Diseases; Neurocognitive Disorders; Mental Disorders; Chronobiology Disorders; Dyssomnias; Sleep Wake Disorders; Occupational Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: SUPPORTIVE CARE
• Intervention Model: SEQUENTIAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 15, 2026
• First Posted: February 4, 2026
• Study Start: January 9, 2026
• Primary Completion (Estimated): October 31, 2026
• Study Completion (Estimated): December 31, 2026
• Last Updated: February 4, 2026

Record last verified: 2026-01

Locations

TW (1)