Investigation of the Effects of Vestibular Rehabilitation and Dynamic Neuromuscular
Dynamic
1 other identifier
interventional
45
1 country
1
Brief Summary
This study will aim to investigate the effects of vestibular rehabilitation, dynamic neuromuscular stabilization (DNS), and conservative rehabilitation exercises on balance and mobility in hemiplegic patients, and to compare the exercise programs with one another. Evaluation tools include the Brunnstrom Motor Staging, Fugl-Meyer Upper Extremity Motor Function Scale, Modified Ashworth Scale, Mini-Mental State Examination, Berg Balance Scale, Stroke Impact Scale, and Timed Up and Go test.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Jan 2026
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 17, 2026
CompletedFirst Submitted
Initial submission to the registry
January 28, 2026
CompletedFirst Posted
Study publicly available on registry
February 4, 2026
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 1, 2026
CompletedStudy Completion
Last participant's last visit for all outcomes
April 1, 2026
CompletedFebruary 4, 2026
January 1, 2026
1 month
January 28, 2026
January 28, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (6)
The Fugl-Meyer Assessment of Upper Extremity
It is a standardized, stroke-specific, performance-based outcome measure used in clinical trials to evaluate motor recovery of the upper limb. It assesses movement, coordination, and reflex activity of the shoulder, elbow, forearm, wrist, and hand, providing a quantitative measure of motor impairment and recovery over time. The maximum score for the arm section is 36. During the finger-to-nose test, coordination and speed of movement are evaluated out of 6 points, while tremor, dysmetria, and speed of movement in the upper extremity are also examined in detail.
From the beginning of treatment to the end of the 6th week
Modified Ashworth Scale (MAS)
It is a widely used clinical outcome measure in clinical trials to assess spasticity by grading the resistance encountered during passive muscle stretching. The joint is passively moved with repetitive and rapid movements, and the joint's resistance to these movements is scored.
From the beginning of treatment to the end of the 6th week
Mini-Mental State Examination (MMSE)
It is a brief, standardized cognitive screening tool used in clinical trials to assess global cognitive function, including orientation, attention, memory, language, and visuospatial abilities. The total score ranges from 0 to 30, with higher scores indicating better cognitive performance. Scores of 24-30 indicate normal cognition, 18-23 mild cognitive impairment, and ≤17 moderate to severe cognitive impairment.
From the beginning of treatment to the end of the 6th week
Berg Balance Scale (BBS)
This is a 14-item scale that assesses a patient's ability to maintain balance for a specific period during static and various functional movements. The scoring system ranges from 0 to 4, with 0 meaning "cannot" and 4 meaning "can do independently," and the maximum total score is 56. A total score between 0-20 indicates a high risk of falls; between 21-40 indicates a moderate risk of falls; and between 41-56 indicates a low risk of falls.
From the beginning of treatment to the end of the 6th week
Stroke Impact Scale (SIS)
It is a stroke-specific, patient-reported outcome measure widely used in clinical trials to evaluate the perceived impact of stroke on multiple domains of health-related quality of life. Based on the obtained score, 0 indicates no recovery, whereas 100 represents complete recovery.
From the beginning of treatment to the end of the 6th week
Timed Up and Go (TUG)
The test is a simple and widely used functional mobility assessment in clinical trials. It measures the time required for an individual to stand up from a chair, walk 3 meters, turn around, walk back, and sit down. Shorter completion times indicate better functional mobility and balance, and the test is commonly used to assess fall risk and mobility limitations.
From the beginning of treatment to the end of the 6th week
Study Arms (3)
Group 1: Conventional Exercise Group
EXPERIMENTALConventional Exercise will be conducted in this group
Group 2: Dynamic Neuromuscular Stabilization Group
EXPERIMENTALDynamic Neuromuscular Stabilization exercises will be done in this group
Group 3: Vestibular Rehabilitation Group
EXPERIMENTALVestibular Rehabilitation will be conducted in this group
Interventions
This group participated in Conventional Exercise programs twice a week for six weeks.
This group participated in Dynamic Neuromuscular Stabilization Exercise programs twice a week for six weeks.
This group participated in Vestibular Rehabilitation programs twice a week for six weeks.
Eligibility Criteria
You may qualify if:
- Being 18 years of age or older
- Having experienced at least one stroke and presenting with hemiplegic symptoms
- Having passed at least one year since the stroke even
- Scoring at least 24 points on the Mini-Mental State Examination (MMSE)
- Being able to walk independently for at least 30 meters without assistance
- Being able to comply with and participate in the exercise program
You may not qualify if:
- Individuals with chronic pulmonary and/or cardiac diseases
- Presence of uncontrolled hypertension
- Conditions accompanied by peripheral nerve injury or lower motor neuron disorders
- Presence of additional neurological disorders such as ataxia, dyskinesia, or dystonia
- Severe spasticity, peripheral lesions, pressure ulcers, marked muscle atrophy, obesity, skin irritation, or use of a cardiac pacemaker
- Presence of vestibular symptoms such as vertigo or dizziness
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Istanbul Medipol University
Istanbul, Turkey (Türkiye)
Related Publications (1)
Yoon HS, Cha YJ, You JSH. Effects of dynamic core-postural chain stabilization on diaphragm movement, abdominal muscle thickness, and postural control in patients with subacute stroke: A randomized control trial. NeuroRehabilitation. 2020;46(3):381-389. doi: 10.3233/NRE-192983.
PMID: 32250328RESULT
Related Links
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
MERVE YILMAZ MENEK
Medipol University
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- OUTCOMES ASSESSOR
- Masking Details
- Outcomes Assessor will be masked in the assesment part in the study.
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Assoc. Prof
Study Record Dates
First Submitted
January 28, 2026
First Posted
February 4, 2026
Study Start
January 17, 2026
Primary Completion
March 1, 2026
Study Completion
April 1, 2026
Last Updated
February 4, 2026
Record last verified: 2026-01
Data Sharing
- IPD Sharing
- Will not share
Individual participant data (IPD) will be made available to other researchers upon reasonable request, if deemed necessary.