Trials Sponsors Conditions Drugs Pricing

Conditions

Soft Tissue Defects Soft Tissue Wounds Traumatic Soft Tissue Defect

Keywords

Traumatic WoundsSoft Tissue RepairNegative Pressure Wound TherapyOvine Forestomach MatrixWound Healing

Outcome Measures

Primary Outcomes (1)

Tissue Coverage
Time (days) to complete tissue coverage of the exposed structure
Up to 56 days/ 8 week follow up

Secondary Outcomes (4)

Complete coverage of exposed structures
up to 28 days (4 weeks)
Post operative complications
Up to 56 days/ 8 week follow up
NPWT Usage

Study Arms (2)

Interventional Arm

EXPERIMENTAL

Myriad™ applied in conjunction with NPWT ('Myriad+NPWT')

Device: Myriad™ applied in conjunction with NPWT

Control Arm

ACTIVE COMPARATOR

NPWT alone ('NPWT')

Device: NPWT Alone

Interventions

Myriad™ applied in conjunction with NPWTDevice

Myriad™ applied in conjunction with NPWT ('Myriad+NPWT')

Interventional Arm

NPWT AloneDevice

Control Arm: NPWT alone ('NPWT')

Control Arm

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age18 Years+

Sexall

Healthy VolunteersNo

Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

Patients will be considered eligible for the study based on the following criteria:
Willing and able to provide written informed consent and to comply with the requirements of the Clinical Investigational Plan

Sponsors & Collaborators

Aroa Biosurgery Limited
Industrylead
Coalition for National Trauma Research
Othercollaborator

Study Sites (2)

University of Colorado-Anschutz Medical Campus

Aurora, Colorado, 80045, United States

RECRUITING

Alyssa Caldwell-McGeeCONTACT303-517-2669 alyssa.caldwell-mcgee@cuanschutz.edu

Tracey MacDermottCONTACT(303)724-2757 TRACEY.MACDERMOTT@CUANSCHUTZ.EDU

Michael Cripps, MDPRINCIPAL INVESTIGATOR

The University of Texas Health Science Center at San Antonio

San Antonio, Texas, 78229, United States

MeSH Terms

Interventions

Negative-Pressure Wound Therapy

Intervention Hierarchy (Ancestors)

DrainageTherapeuticsSurgical Procedures, OperativeWound Closure Techniques

Study Officials

Julie Rizzo, MD
Brooke Army Medical Center
PRINCIPAL INVESTIGATOR

Central Study Contacts

Lizette Villarreal, MA

CONTACT

2107182308 Lizette@NatTrauma.org

Serina Zorilla, MSN

CONTACT

7039300041

Study Design

Study Type: interventional
Phase: phase 4
Allocation: RANDOMIZED
Masking: NONE
Masking Details: Investigators cannot be blinded to the treatment groups
Purpose: TREATMENT
Intervention Model: PARALLEL
Sponsor Type: INDUSTRY
Responsible Party: SPONSOR

Study Record Dates

First Submitted

January 27, 2026

First Posted

February 4, 2026

Study Start

March 31, 2026

Actual (reported)

Combined OFM and Vacuum-assisted Therapy for Expedited Regeneration Over Structures

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

First Submitted

First Posted

Study Start

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (4)

Study Arms (2)

Interventional Arm

Control Arm

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (2)

MeSH Terms

Interventions

Intervention Hierarchy (Ancestors)

Study Officials

Central Study Contacts

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

First Submitted

First Posted

Study Start

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (4)

Study Arms (2)

Interventional Arm

Control Arm

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (2)

MeSH Terms

Interventions

Intervention Hierarchy (Ancestors)

Study Officials

Central Study Contacts

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations