Treatment Strategy for Complicated Pediatric Appendicitis Based on Laparoscopic Surgery

NCT07385261 | Completed

• 1 other identifier: SUV-MED- SUR011-4-25-3-2
• Study Type: interventional
• Target: 765
• Locations: 1 country
• Sites: 1

Brief Summary

Observational retrospective study included 765 children with Operative management by laparoscopic appendectomy, conservative management for appendicular mass and drainage of abscess by IR should be tried first. Interval appendectomy is reserved only for patients with recurrent symptoms. the study collect the Diagnostic data ,intraoperative and post operative data to submit the strategies of laparoscopic management in limited resources setting.

Conditions

Appendix Diseases; Surgery

Keywords

laparoscopic surgery; complicated appendicitis

Outcome Measures

Primary Outcomes (1)

• Primary outcomes

  postoperative outcomes any alarming symptoms of intestinal obstruction developed (vomiting, fever, or severe abdominal pain, intraperitoneal collections

  4 years

Study Arms (1)

Complicated Appendicitis

EXPERIMENTAL

Complicated appendicitis: refer to acute appendicitis with perforation or gangrene, appendicular mass with or without abdominal abscess formation submitted for laparoscopic management with appendectomy and intraperitoneal suction of pus over the last 10 years

Procedure: laparoscopic appendectomy

Interventions

laparoscopic appendectomy PROCEDURE

Based on clinical findings, imaging studies and laboratory findings, after resuscitation, the decision of urgent surgery was according to the presentation Free peritoneal perforation (FPA) Perforated appendicitis with free peritoneal fluid were managed by urgent laparoscopic exploration Appendicular mass (AM) In patients presented by early mass formation lap exploration was carried out but trial of conservative management was planned for cases presented late with expected difficulty in lap dissection depending on surgical team and parental consultation, this accomplished by (nothing per mouth, I V fluid, I V antibiotic, temperature chart with U/S and biomarker follow up) Appendicular abscess (AAbs) Percutaneous drainage by availability IR team was the first choice however lap exploration and /or lap assisted extraperitoneal drainage was the second choice if IR failed or not available.

Complicated Appendicitis

Eligibility Criteria

• Age: Up to 18 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• laparoscopic management of Complicated Appendicitis with mass formation
• laparoscopic management of Complicated appendicitis with abscess formation:
• laparoscopic management of Complicated appendicitis with free intraperitoneal collection

You may not qualify if:

• Open surgery cases
• Patients received incomplete antibiotic therapy
• Accidental discovery coexistent pathology that necessitates open surgery

Sponsors & Collaborators

• Mohammad Daboos: lead
• South Valley University: collaborator
• Tanta University: collaborator

Study Sites (1)

Mohammad Daboos

Cairo, 115678, Egypt

Location

Study Officials

• ‪Mohammad Daboos‬, Dr

  Department of pediatric surgery, faculty of medicine , Al-Azhar University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Assistant professor of pediatric surgery, Faculty of Medicine, Al-Azhar University

Model Details: Single Group Assignment Pediatric patients aged less than 18 years, with Complicated appendicitis (with mass, appendicular abscess, and free collection) received surgical intervention with laparoscopy

Study Record Dates

• First Submitted: January 27, 2026
• First Posted: February 4, 2026
• Study Start: January 1, 2015
• Primary Completion: January 1, 2025
• Study Completion: January 1, 2026
• Last Updated: February 4, 2026

Record last verified: 2026-01

Locations

EG (1)