NCT07381153

Brief Summary

This study aims to evaluate the cytotoxicity of INOX (Nanoksa G Plus) high-performance polymer discs on cell cultures using standardized in-vitro assays. The primary objective is to assess cell viability after exposure to INOX extracts. Secondary objectives include examining cell membrane integrity, cellular morphology, comparing effects across extract concentrations, and determining whether INOX meets accepted non-cytotoxicity standards.

Trial Health

63
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at below P25 for all trials

Timeline
0mo left

Started Jan 2027

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 24, 2026

Completed
9 days until next milestone

First Posted

Study publicly available on registry

February 2, 2026

Completed
12 months until next milestone

Study Start

First participant enrolled

January 20, 2027

Expected
5 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 25, 2027

5 days until next milestone

Study Completion

Last participant's last visit for all outcomes

January 30, 2027

Last Updated

March 19, 2026

Status Verified

January 1, 2026

Enrollment Period

5 days

First QC Date

January 24, 2026

Last Update Submit

March 17, 2026

Conditions

Cytotoxicity

Keywords

INOXNanoksa G PlusINVITRO

Outcome Measures

Primary Outcomes (1)

  • Cell viability

    Cell viability, assessed using a quantitative assay (MTT, XTT, or Alamar Blue).

    JANUARY 2026

Eligibility Criteria

Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Invitro study to evaluate the cytotoxicity of INOX (Nanoksa G Plus) high-performance polymer discs on cell cultures using standardized in-vitro assays.

You may qualify if:

  • To assess cell viability following exposure to INOX material extracts using a quantitative cell viability assay.

You may not qualify if:

  • To evaluate cell membrane integrity following exposure to INOX extracts. To assess cellular morphology after exposure to the material. To compare cytotoxic effects at different extract concentrations. To determine whether INOX meets accepted non-cytotoxicity thresholds.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Cairo university

Giza, Egypt

Location

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Lecturer of Periodontology, Faculty of Dentistry, Cairo University , Cairo, Egypt

Study Record Dates

First Submitted

January 24, 2026

First Posted

February 2, 2026

Study Start (Estimated)

January 20, 2027

Primary Completion (Estimated)

January 25, 2027

Study Completion (Estimated)

January 30, 2027

Last Updated

March 19, 2026

Record last verified: 2026-01

Locations

EG(1)