NCT07381010

Brief Summary

The goal of is project is to improve caregiver education about the behavioral and psychological symptoms (BPSD) of dementia. This intervention will incorporate principles from the science of learning for structuring retrieval practice to optimize learning and long-term retention of key health information. The processing-knowledge model for ADRD care predicts that enhancing health knowledge using structured retrieval practice will best support caregivers of people living with dementia (PLwD).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
73

participants targeted

Target at P75+ for phase_1

Timeline
Completed

Started Jan 2025

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2025

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2025

Completed
24 days until next milestone

First Submitted

Initial submission to the registry

January 24, 2026

Completed
9 days until next milestone

First Posted

Study publicly available on registry

February 2, 2026

Completed
Last Updated

February 2, 2026

Status Verified

January 1, 2026

Enrollment Period

12 months

First QC Date

January 24, 2026

Last Update Submit

January 24, 2026

Conditions

Dementia

Keywords

dementia caresymptoms of dementiacaregiver knowledge

Outcome Measures

Primary Outcomes (2)

  • Delayed test performance

    Proportion correct on the final 2-day delayed test of symptoms and treatments of ADRD. The test was in multiple-choice format. Performance was explored via percent correct on the test, magnitude of the retrieval practice effect on the test, and amount of forgetting.

    2 days after baseline

  • Immediate test performance

    Proportion correct on the immediate (approx. 10 min retention interval) test of symptoms and treatments of ADRD. The test was multiple-choice format. Performance was explored via percent correct on the test, magnitude of the retrieval practice effect on the test, and amount of forgetting.

    Baseline

Secondary Outcomes (12)

  • Caregiver Self-efficacy

    pre-intervention and 2-days post baseline

  • E-Health Literacy

    2 days after baseline

  • Letter and pattern comparison

    2 days after baseline

  • Raven's Progressive Matrices

    Baseline

  • Vocabulary

    2 days after baseline

  • +7 more secondary outcomes

Study Arms (2)

Structured Retrieval Practice (SRP) intervention

EXPERIMENTAL
Behavioral: Structured Retrieval Practice (SRP)

Active Control Comparison

ACTIVE COMPARATOR

Rereading

Behavioral: Standard Health Education

Interventions

Structured Retrieval Practice (SRP)BEHAVIORAL

Our Structured Retrieval Practice (SRP) Caregiver Intervention is a web-based multi-media program designed to enhance dementia caregivers' goal-relevant memory, reduce caregiver stress, and reduce perceptions of symptom severity. The self-guided online intervention does not require supervision by a healthcare professional. Caregivers learn modules on dementia care and complete dynamic multiple-choice tests targeting practical knowledge supported with detailed, elaborative feedback to correct health misconceptions.

Structured Retrieval Practice (SRP) intervention
Standard Health EducationBEHAVIORAL

Caregivers re-read modules on Alzheimer's Disease or related dementias (ADRD) in a webpage format, as would be available from online resources (e.g., National Institutes of Health) to mirror how most caregivers obtain information.

Active Control Comparison

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Caregiver for a person living with dementia
  • Read and speak English
  • Free from cognitive impairments that prevent consenting or completing experimental tasks

You may not qualify if:

  • Technology issues (e.g., loss of internet connection)
  • Not finishing the study
  • Significant distractions
  • Failing 2 or more attention or bot checks
  • Response times 3+ standard deviations from the mean for time sensitive measures
  • Completing session 1 in less than 1 hour

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Texas Christian University

Fort Worth, Texas, 76129, United States

Location

Virginia Wesleyan University

Norfolk, Virginia, 23502, United States

Location

MeSH Terms

Conditions

Dementia

Condition Hierarchy (Ancestors)

Brain DiseasesCentral Nervous System DiseasesNervous System DiseasesNeurocognitive DisordersMental Disorders

Study Design

Study Type
interventional
Phase
phase 1
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
Masking Details
Participants will be masked to study hypotheses.
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Model Details: Randomized controlled trial with caregivers randomly assigned to either the treatment (intervention) or active control comparison.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

January 24, 2026

First Posted

February 2, 2026

Study Start

January 1, 2025

Primary Completion

December 31, 2025

Study Completion

December 31, 2025

Last Updated

February 2, 2026

Record last verified: 2026-01

Data Sharing

IPD Sharing
Will share
Shared Documents
STUDY PROTOCOL, SAP, ICF, CSR, ANALYTIC CODE

Locations

US(2)