NCT07380906|Recruiting
geniculaR Artery eMBolization for Knee Osteoarthritis (RAMBO) Registry
RAMBO
Creation Of a Prospective Registry For Genicular Artery Embolization At The Joint & Vascular Institute
Loading search results
RAMBO
Creation Of a Prospective Registry For Genicular Artery Embolization At The Joint & Vascular Institute
Sponsor study identifier
observational
1,200
1 country
1
Study Start
July 16, 2025
Actual (reported)Primary Completion
April 2030
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Study Completion
July 2030
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
The goal of this observational study (prospective registry) is to collect long-term real-world data on the effectiveness and safety of genicular artery embolization (GAE) for knee osteoarthritis in adults aged 18 years or older with symptomatic KOA that has not responded to medical therapy. The main questions it aims to answer are:
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
July 2030
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
July 16, 2025
Actual (reported)January 24, 2026
Actual (reported)February 2, 2026
Actual (reported)April 2030
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
July 2030
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)
The investigators will describe differences in pain response with Genicular Artery Embolization (GAE) compared to a sham procedure when treating medically refractory mild to moderate Knee Osteoarthritis (KOA) at 12 months as measured by the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Pain subscale score. A higher score index a higher pain level while a lower score indicates lower pain levels. The score range is 0 to 96.
5 years of enrollment/patient
Genicular Artery Embolization (GAE) is a minimally invasive, image-guided procedure in which embolic agents are delivered into hyperemic genicular arteries to reduce synovial inflammation and knee pain from osteoarthritis.
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
The study population consists of adult patients (18 years and older) presenting to the Joint \& Vascular Institute for clinical consultation regarding symptomatic knee osteoarthritis. This population includes individuals who have failed standard medical management and are seeking minimally invasive alternatives to total knee arthroplasty. The registry will include men and women of all races and ethnicities without exclusion, provided they meet the clinical criteria for GAE as determined by the Principal Investigator or Sub-Investigators.
Joint and Vascular Institute
Libertyville, Illinois, 60048, United States
First Submitted
January 24, 2026
First Posted
February 2, 2026
Study Start
July 16, 2025
Actual (reported)Primary Completion
April 2030
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Contact the study team to confirm eligibility.
Study Completion
July 2030
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Last Updated
June 12, 2026
Record last verified: 2026-06
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.
Source retrieved: