Improving Uptake of Bowel Cancer Screening Among South Asian Adults in Bradford

NCT07376694 | Active Not Recruiting

• 1 other identifier: RS213-332905
• Study Type: interventional
• Target: 2,300
• Locations: 1 country
• Sites: 1

Brief Summary

Bowel cancer is the second most common cause of cancer related deaths in England. Bowel cancer screening can reduce bowel cancer deaths by detecting bowel cancer early. Previous research has shown that screening can lower a person's risk of dying from bowel cancer by over 25%. In England, the NHS offers free bowel cancer screening for adults aged 60 - 74 years who are registered with a GP every two years, but screening uptake remains poor among those in deprived areas and amongst minority ethnic groups. In socioeconomically deprived areas like Bradford, where there is a high proportion of South Asian residents, bowel cancer screening uptake is low compared to other parts of England. The investigators previous research has shown that people of South Asian ethnicity are limited by many factors beyond language barriers and thus require culturally tailored approaches to facilitate uptake. For this study, the investigators will aim to answer the question: 'Does a culturally tailored enhanced screening kit, comprising an instruction letter and booklet, and a bio-degradable poo catcher increase bowel cancer screening uptake among South Asians living in Bradford?'. Over a 6-month period, individuals registered in 17 GP practices in Bradford and due to receive their NHS bowel cancer screening invitation will be assigned to two groups: standard kit (usual screening kit only) and enhanced kit (culturally tailored instruction letter and biodegradable poo catcher). Uptake of bowel cancer screening among South Asian participants in each group will be assessed 13 weeks after the identification of the final participant. The findings of this study will provide valuable information for policy makers about how to address population specific barriers to bowel cancer screening using culturally tailored approaches in the UK.

Conditions

Bowel Cancer Screening

Keywords

Screening; FOBT; non-randomised trial; South Asian; FIT

Outcome Measures

Primary Outcomes (1)

• Return of bowel screening kit for testing

  % of individuals who return their bowel screening kit for foecal immunochemical testing measured using data recorded in their clinical records

  13 weeks (screening episode)

Secondary Outcomes (1)

• Bowel cancer screening test result

  13 weeks (screening episode)

Other Outcomes (3)

• Practicality of implementation of the enhanced kit

  13 weeks (screening episode)

• Costs

  13 weeks (screening episode)

• Acceptability of implementation of enhanced kit

  13 weeks (screening episode)

Study Arms (2)

Enhanced screening kit

EXPERIMENTAL

Culturally tailored enhanced screening kit, comprising an instruction letter and booklet, and a bio-degradable poo catcher

Other: Bowel cancer screening kit

Usual kit

ACTIVE COMPARATOR

Screening kit only

Other: Bowel cancer screening kit

Interventions

Bowel cancer screening kit OTHER

Home Fecal Occult Blood Test kit

Also known as: FOBT

Enhanced screening kit; Usual kit

Eligibility Criteria

• Age: 50 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients registered with one of 17 participating GP practices in Bradford
• Patients invited for bowel cancer screening during the implementation period

You may not qualify if:

• \) Individuals who are self-referrals 2) Type 2 objectors

Sponsors & Collaborators

• Gateshead Health NHS Foundation Trust: collaborator
• Bradford Teaching Hospitals NHS Foundation Trust: collaborator
• University of Hull: lead

Study Sites (1)

Northeast Bowel cancer Screening Hub

Gateshead, Yorkshire, United Kingdom

Location

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: SCREENING
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: January 12, 2026
• First Posted: January 29, 2026
• Study Start: November 1, 2024
• Primary Completion: April 1, 2026
• Study Completion (Estimated): June 30, 2026
• Last Updated: January 29, 2026

Record last verified: 2025-11

Data Sharing

• IPD Sharing: Will not share

Locations

GB (1)