NCT07376005

Brief Summary

This study aims to bridge that gap by investigating how acute sugar intake influences choroidal thickness.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
47

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jan 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2026

Completed
20 days until next milestone

First Submitted

Initial submission to the registry

January 21, 2026

Completed
8 days until next milestone

First Posted

Study publicly available on registry

January 29, 2026

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2026

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2026

Completed
Last Updated

January 29, 2026

Status Verified

January 1, 2026

Enrollment Period

4 months

First QC Date

January 21, 2026

Last Update Submit

January 21, 2026

Conditions

Choroid

Outcome Measures

Primary Outcomes (1)

  • Change in choroidal thickness

    The primary outcome for this investigation will be changes in choroidal thickness from baseline across timepoints.

    within 3 hours of baseline

Study Arms (1)

Oral glucose

ACTIVE COMPARATOR

Subjects receive 30g of oral glucose

Dietary Supplement: Oral glucose

Interventions

Oral glucoseDIETARY_SUPPLEMENT

Participants will consume 30 grams of sugar in the form of glucose tablets.

Oral glucose

Eligibility Criteria

Age21 Years - 35 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • In order to be eligible for enrolment, each subject must have less than 6 diopters of spherical equivalent refractive error, and have no existing diagnosis of diabetes or pre-diabetes.

You may not qualify if:

  • Any potential subject with known retinal pathology will be excluded. Any potential subject with any other known systemic or ocular conditions that may impact their ability to participate in the study or provide generalizable data will also be excluded.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Southern College of Optometry

Memphis, Tennessee, 38111, United States

RECRUITING

MeSH Terms

Interventions

Glucose

Intervention Hierarchy (Ancestors)

HexosesMonosaccharidesSugarsCarbohydrates

Central Study Contacts

Morgan Ollinger, OD, MS

CONTACT

9017223377mollinger@sco.edu

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
OTHER
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 21, 2026

First Posted

January 29, 2026

Study Start

January 1, 2026

Primary Completion

May 1, 2026

Study Completion

May 1, 2026

Last Updated

January 29, 2026

Record last verified: 2026-01

Locations

US(1)