HbA1c Levels and Gastric Emptying Assessed by Gastric Ultrasound

NCT07375680 | Recruiting

• 1 other identifier: KHSU-HbA1c-GastricUS
• Study Type: observational
• Target: 134
• Locations: 1 country
• Sites: 1

Brief Summary

Delayed gastric emptying increases the risk of pulmonary aspiration during general anesthesia. Diabetes mellitus and poor long-term glycemic control have been associated with impaired gastric motility. Hemoglobin A1c (HbA1c) is a marker of long-term glycemic control; however, its relationship with gastric emptying in surgical patients is not fully understood. This prospective observational study aims to evaluate the association between HbA1c levels and gastric emptying using preoperative bedside gastric ultrasonography. Adult patients scheduled for elective surgery under general anesthesia will undergo gastric ultrasound examination after standard fasting. Gastric antral cross-sectional area and estimated gastric volume will be assessed and compared according to HbA1c levels. The findings of this study may help improve preoperative risk stratification for aspiration and support individualized anesthetic management in patients with impaired glycemic control.

Conditions

Delayed Gastric Emptying; Diabetes Mellitus; Pulmonary Aspiration

Keywords

Hemoglobin A1c; Gastric Ultrasonography; General Anesthesia; Preoperative Assessment

Outcome Measures

Primary Outcomes (1)

• Gastric emptying assessed by gastric ultrasound

  Gastric emptying will be assessed preoperatively using bedside gastric ultrasonography by measuring gastric antrum cross-sectional area and estimating gastric volume with validated ultrasound-based methods.

  The preoperative period,immediately before induction of anesthesia

Study Arms (1)

Study Population

Adult patients scheduled for elective surgery under general anesthesia who undergo preoperative bedside gastric ultrasonography as part of an observational study.

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adult patients aged 18 to 70 years scheduled for elective surgery under general anesthesia at a tertiary care hospital.

You may qualify if:

• Adults aged 18 to 70 years. ASA physical status I-III. Scheduled for elective surgery under general anesthesia. Ability to provide written informed consent.

You may not qualify if:

• Scheduled for emergency surgery. Refusal or inability to provide informed consent. Pregnancy. Age \<18 years or \>70 years. History of gastric surgery. Neuromuscular disease. Current use of opioid or anticholinergic medications.

Sponsors & Collaborators

• Kutahya Health Sciences University: lead

Study Sites (1)

Kutahya Health Science University Training and Research Hospital

Kütahya, Kütahya, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Gastroparesis; Diabetes Mellitus

Condition Hierarchy (Ancestors)

Stomach Diseases; Gastrointestinal Diseases; Digestive System Diseases; Paralysis; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Endocrine System Diseases

Study Officials

• merve yaman, MD, Assistant Professor

  Kutahya Health Science University

  PRINCIPAL INVESTIGATOR

• emine gök, MD

  Kutahya Health Science University

  STUDY DIRECTOR

Central Study Contacts

merve yaman, MD, Assistant Professor

CONTACT

+905363794742; merve.yaman@ksbu.edu.tr

emine gök, MD

CONTACT

+905050270167; emine.gok@ksbu.gov.tr

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: MD,Assistant Professor of Anesthesiology

Study Record Dates

• First Submitted: January 22, 2026
• First Posted: January 29, 2026
• Study Start: February 15, 2026
• Primary Completion (Estimated): August 15, 2026
• Study Completion (Estimated): September 1, 2026
• Last Updated: April 8, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)