Frailty and Chronic Pain Profiles in Patients Aged ≥65 Years

NCT07373860 | Completed

• 1 other identifier: TABED-1-25-1637
• Study Type: observational
• Target: 393
• Locations: 1 country
• Sites: 1

Brief Summary

The primary aim of this study is to investigate the relationship between frailty status and pain type, pain localization, and the Geriatric Nutritional Risk Index (GNRI) in individuals aged 65 years and older who present to an pain clinic with chronic pain. The secondary aim is to evaluate the level of interaction among these parameters and to contribute to a holistic approach to pain management in older adults.

Conditions

Geriatric Pain

Keywords

chronical pain; neuropathic pain; Nociceptive Pain

Outcome Measures

Primary Outcomes (1)

• primary outcome

  Frailty status determined according to the Fried Frailty Criteria (Frailty Phenotype). Frailty will be classified as robust (0 criteria), pre-frail (1-2 criteria), or frail (≥3 criteria) based on the presence of unintentional weight loss, exhaustion, low physical activity, slowness, and weakness.

  baseline

Secondary Outcomes (6)

• Secondary outcome

  baseline

• Secondary Outcome Measure

  baseline

• Secondary outcome meaaure

  Baseline

• Secondary outcome

  Baseline

• Secondary outcome

  During the 3-month follow-up period.

Study Arms (1)

Elderly Chronic Pain Cohort

The Elderly Chronic Pain Cohort consisted of individuals aged 65 years and older who presented to the pain outpatient clinic with complaints of chronic pain and met the study inclusion criteria. All eligible participants were consecutively enrolled during the study period. Frailty status, nutritional risk, and pain-related characteristics were systematically assessed at baseline. Subgroup analyses were performed according to frailty statu

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients who have chronical pain for more than months and older than 65 years old

You may qualify if:

• Age 65 years or older Diagnosis of chronic pain (duration \> 3 months)

You may not qualify if:

• Acute pain complaint Pain related to malignancy Severe communication impairment

Sponsors & Collaborators

• Ankara City Hospital Bilkent: lead

Study Sites (1)

Ankara Bilkent City Hospital

Ankara, Cankaya, Turkey (Türkiye)

Location

Related Publications (1)

• Saito T, Liu X, Yatsugi H, Chu T, Yokote T, Kishimoto H. Relationship Between Chronic Pain Types (Nociceptive and Neuropathic-Like Symptoms) and Frailty in Community-Dwelling Japanese Older Adults: A Cross-Sectional Study. J Pain Res. 2023 Aug 1;16:2675-2684. doi: 10.2147/JPR.S402002. eCollection 2023.

  PMID: 37545692 RESULT

MeSH Terms

Conditions

Neuralgia; Nociceptive Pain

Condition Hierarchy (Ancestors)

Peripheral Nervous System Diseases; Neuromuscular Diseases; Nervous System Diseases; Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 1 Day
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assoc. prof.

Study Record Dates

• First Submitted: January 15, 2026
• First Posted: January 28, 2026
• Study Start: January 1, 2026
• Primary Completion: May 12, 2026
• Study Completion: May 12, 2026
• Last Updated: May 13, 2026

Record last verified: 2026-05

Locations

TU (1)