NCT07369843

Brief Summary

This study investigate the potential impact of low power laser (LPL), an non-invasive physical therapy, on the cardiovascular system by focusing on its effect on heart rate and autonomic tone. Study will recruit healthy volunteers and non-invasively monitor their electrocardiogram and digital pulse in response to LPL. In addition, the potential involvement of autonomic tone will be clarify by topically applying gel (2% lidocaine gel)

Trial Health

65
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
45

participants targeted

Target at P25-P50 for not_applicable

Timeline
1mo left

Started Mar 2026

Shorter than P25 for not_applicable

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress75%
Mar 2026May 2026

First Submitted

Initial submission to the registry

September 26, 2025

Completed
4 months until next milestone

First Posted

Study publicly available on registry

January 27, 2026

Completed
1 month until next milestone

Study Start

First participant enrolled

March 1, 2026

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 30, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 30, 2026

Last Updated

January 27, 2026

Status Verified

July 1, 2025

Enrollment Period

3 months

First QC Date

September 26, 2025

Last Update Submit

January 18, 2026

Conditions

Pain Management

Keywords

low power LASERHeart rateautonomic tone

Outcome Measures

Primary Outcomes (1)

  • heart rate

    the heart rate before, during, and after low power LASER

    Continuous heart rate (HR) recording will start when it is stable after a brief resting (10 min); maintained during stimulation (30 min), and lasted for a period until the HR recovers.

Study Arms (1)

test effect

EXPERIMENTAL

Control, experiment, and recovery data will be acquired for each volunteer

Other: physical therapy (low power LASER)

Interventions

physical therapy (low power LASER)OTHER

Low power laser with an intensity for pain relieving will be applied to volunteers

test effect

Eligibility Criteria

Age20 Years - 45 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • age from 20-45

You may not qualify if:

  • no medical history of diabetes, hypertension, or other medical problem

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Agnosia

Interventions

Physical Therapy Modalities

Condition Hierarchy (Ancestors)

Perceptual DisordersNeurobehavioral ManifestationsNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

TherapeuticsRehabilitation

Central Study Contacts

Chun-Ming Hsieh, MS

CONTACT

+886-(03)361-3141tblin2@gmail.com

Tzer-Bin Lin, Ph.D.

CONTACT

+886-0935-972505

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 26, 2025

First Posted

January 27, 2026

Study Start

March 1, 2026

Primary Completion (Estimated)

May 30, 2026

Study Completion (Estimated)

May 30, 2026

Last Updated

January 27, 2026

Record last verified: 2025-07