NCT07366398

Brief Summary

Patients were instructed to use 2 different mouthwashes after performing professional tooth cleaning. The effect of each of the 2 mouthwashes was detected.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
16

participants targeted

Target at below P25 for phase_3

Timeline
Completed

Started Feb 2025

Shorter than P25 for phase_3

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2025

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 30, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 30, 2025

Completed
8 months until next milestone

First Submitted

Initial submission to the registry

January 17, 2026

Completed
9 days until next milestone

First Posted

Study publicly available on registry

January 26, 2026

Completed
Last Updated

January 26, 2026

Status Verified

January 1, 2026

Enrollment Period

4 months

First QC Date

January 17, 2026

Last Update Submit

January 23, 2026

Conditions

Gingivitis; Chronic

Outcome Measures

Primary Outcomes (1)

  • Bleeding on probing

    % of gingival sites where bleeding occurred on periodontal probing is registered out of total gingival sites

    7 days

Secondary Outcomes (2)

  • Plaque index

    7 days

  • Patient's satisfaction questionnaire

    7 days

Study Arms (2)

Chlorhexidine mouthwash

ACTIVE COMPARATOR
Drug: Chlorhexidine 0,12%

Hyaluronic acid + Chlorhexidine mouthwash

ACTIVE COMPARATOR
Drug: Hyaluoric acid mouthwashDrug: Chlorhexidine 0,12%

Interventions

Hyaluoric acid mouthwashDRUG

A mouthwash containing both hyaluronic acid

Hyaluronic acid + Chlorhexidine mouthwash
Chlorhexidine 0,12%DRUG

mouthwash of chlorhexidine 0.12%

Chlorhexidine mouthwashHyaluronic acid + Chlorhexidine mouthwash

Eligibility Criteria

Age25 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Diagnosed with gingivitis

You may not qualify if:

  • pregnant or lactating females and current smokers

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ahram Canadian University

Giza, Egypt

Location

MeSH Terms

Conditions

GingivitisBronchiolitis Obliterans Syndrome

Condition Hierarchy (Ancestors)

InfectionsGingival DiseasesPeriodontal DiseasesMouth DiseasesStomatognathic DiseasesOrganizing PneumoniaBronchiolitis ObliteransBronchiolitisBronchitisBronchial DiseasesRespiratory Tract DiseasesLung Diseases, ObstructiveLung DiseasesGraft vs Host DiseaseImmune System Diseases

Study Design

Study Type
interventional
Phase
phase 3
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
PI

Study Record Dates

First Submitted

January 17, 2026

First Posted

January 26, 2026

Study Start

February 1, 2025

Primary Completion

May 30, 2025

Study Completion

May 30, 2025

Last Updated

January 26, 2026

Record last verified: 2026-01

Locations

EG(1)