NCT07364708

Brief Summary

using a relatively new technique to manage post-cataract surgery complication and measuring its efficacy

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
50

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jul 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 20, 2025

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

December 29, 2025

Completed
3 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2026

Completed
22 days until next milestone

First Posted

Study publicly available on registry

January 23, 2026

Completed
9 days until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2026

Completed
Last Updated

January 23, 2026

Status Verified

July 1, 2025

Enrollment Period

6 months

First QC Date

December 29, 2025

Last Update Submit

January 16, 2026

Conditions

Descemet's Membrane Disorder

Outcome Measures

Primary Outcomes (1)

  • Rate of complete anatomical reduction of DMD on ASOCT at the 1-week visit.

    1 week

Secondary Outcomes (1)

  • . Time to complete anatomical reduction (days)

    1 month

Study Arms (2)

will undergo direct intracameral air injection

OTHER
Procedure: group A will undergo direct intracameral air injection and group B will undergo anterior chamber deflation then intracameral air injection

will undergo anterior chamber deflation then intracameral air injection

OTHER
Procedure: group A will undergo direct intracameral air injection and group B will undergo anterior chamber deflation then intracameral air injection

Interventions

group A will undergo direct intracameral air injection and group B will undergo anterior chamber deflation then intracameral air injectionPROCEDURE

a group will undergo direct intracameral air injection and another group will undergo anterior chamber deflation then intracameral air injection

will undergo anterior chamber deflation then intracameral air injectionwill undergo direct intracameral air injection

Eligibility Criteria

Age50 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients with post cataract surgery DM detachment diagnosed within 1st week postoperatively.
  • Patient age ranges from 50 to 70 years old.

You may not qualify if:

  • Less than one third of Descemet's Membrane is included.
  • Post-operative infection or severe inflammation.
  • Patient with pre-existing glaucoma.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Khalafallah

Minya, None Selected, 61111, Egypt

RECRUITING

Central Study Contacts

Ahmed Maher Khalafallah

CONTACT

+201119094426drahmedmaher1988@gmail.com

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
lecturer of ophthalmology, faculty of medicine, Minia university

Study Record Dates

First Submitted

December 29, 2025

First Posted

January 23, 2026

Study Start

July 20, 2025

Primary Completion

January 1, 2026

Study Completion

February 1, 2026

Last Updated

January 23, 2026

Record last verified: 2025-07

Data Sharing

IPD Sharing
Will share
Shared Documents
STUDY PROTOCOL

Locations

EG(1)