NCT07363863

Brief Summary

the study will discuss different pattern of treatment and the outcomes of locally advanced rectal carcinoma as a retrospective study. The study will be conducted at Department of Clinical Oncology, Sohag University Hospital and Sohag Cancer center, Sohag, Egypt. including patients diagnosed and treated between 2018 and 2025. and the data will be collected from reports .

Trial Health

65
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
5mo left

Started Mar 2026

Shorter than P25 for all trials

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress32%
Mar 2026Oct 2026

First Submitted

Initial submission to the registry

November 27, 2025

Completed
2 months until next milestone

First Posted

Study publicly available on registry

January 23, 2026

Completed
1 month until next milestone

Study Start

First participant enrolled

March 1, 2026

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2026

Expected
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2026

Last Updated

January 23, 2026

Status Verified

November 1, 2025

Enrollment Period

4 months

First QC Date

November 27, 2025

Last Update Submit

January 14, 2026

Conditions

Rectal Carcinoma

Outcome Measures

Primary Outcomes (3)

  • Estimation of overall survival (OS ).

    2018 _ 2025

  • Estimation of Response rate .

    2018-2025

  • Estimation of disease-free survival (DFS) .

    2018-2025

Secondary Outcomes (1)

  • treatment-related toxicity: (graded by CTCAE v5).

    2018-2025

Interventions

No Intervention (subjects were previously treated with Onglyza®)OTHER

no intervention

Eligibility Criteria

Age18 Years - 90 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

The study will be conducted at Department of Clinical Oncology, Sohag University Hospital and Sohag Cancer center, Sohag, Egypt.

You may qualify if:

  • patients who were more than18 years old at time of diagnosis.
  • Patients with histologically confirmed rectal carcinoma.
  • Stage II-III (locally advanced) disease at initial diagnosis.

You may not qualify if:

  • Patients with distant metastasis at presentation.
  • Patients diagnosed with double malignancy.
  • Patients with incomplete medical records.
  • Organ failure

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Rectal Neoplasms

Interventions

saxagliptin

Condition Hierarchy (Ancestors)

Colorectal NeoplasmsIntestinal NeoplasmsGastrointestinal NeoplasmsDigestive System NeoplasmsNeoplasms by SiteNeoplasmsDigestive System DiseasesGastrointestinal DiseasesIntestinal DiseasesRectal Diseases

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
principal investigator

Study Record Dates

First Submitted

November 27, 2025

First Posted

January 23, 2026

Study Start

March 1, 2026

Primary Completion (Estimated)

July 1, 2026

Study Completion (Estimated)

October 1, 2026

Last Updated

January 23, 2026

Record last verified: 2025-11