NCT07362472

Brief Summary

After Standardized anesthetic induction patients were randomly given regional blocks. Group A recieved erecter spinae plane block \& group B recieved combined serratous anterior and pecto-intercoatal facial plane block. Their mean morphine consumption were followed for the next 24 hours.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Nov 2024

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 7, 2024

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 11, 2025

Completed
16 days until next milestone

Study Completion

Last participant's last visit for all outcomes

August 27, 2025

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

January 15, 2026

Completed
8 days until next milestone

First Posted

Study publicly available on registry

January 23, 2026

Completed
Last Updated

January 23, 2026

Status Verified

January 1, 2026

Enrollment Period

9 months

First QC Date

January 15, 2026

Last Update Submit

January 15, 2026

Conditions

Pain ScoreMorphine Consumption

Keywords

Breast surgeriesErecter spinae planeserratous anterior plane

Outcome Measures

Primary Outcomes (1)

  • mean morphine consumption

    We calculated and compared mean morphine consumption in first 24 hours post operatively among the 2 groups.

    24 hours

Secondary Outcomes (1)

  • Pain score

    24 hours

Study Arms (2)

Erecter spinae plane block

ACTIVE COMPARATOR

Ultrasound guided 30ml erecter spinae plane block was provided with standard bupivacaine (2mg/kg)

Procedure: Regional nerve blocks

serratous anterior plane block and pecto-intercoastal facial plane block

ACTIVE COMPARATOR

Ultrasound guided 30ml serratous anterior plane block and pecto-intercoastal facial plane block was provided with standard bupivacaine (2mg/kg)

Procedure: Regional nerve blocks

Interventions

Regional nerve blocksPROCEDURE

In these interventions we compared two regional blocks (serratous anterior \& pecto intercoastal facial plane block) techniques vs one regional block (erecter spinae plane block)

Erecter spinae plane blockserratous anterior plane block and pecto-intercoastal facial plane block

Eligibility Criteria

Age18 Years - 45 Years
Sexfemale(Gender-based eligibility)
Gender Eligibility DetailsBreast cancer surgeries
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Female patients undergoing major breast cancer surgeries (modified radical mastectomy, breast reconstruction with implants).
  • American society of anesthesiologist Grade 1 \& 2
  • Age between 18 to 45 years

You may not qualify if:

  • Patient's refusal
  • Emergency cases
  • Patients having uncontrolled diseases like asthma, COPD or other lung diseases
  • History of allergy from the drugs being used during the study
  • Pregnant patients
  • Patients with coagulopathies/bleeding disorders
  • Patients undergoing bilateral major breast cancer surgery.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Shaukat Khanam Memorial Cancer Hospital & Research Centre Lahore

Lahore, Punjab Province, Pakistan

Location

Related Publications (1)

  • Finnerty DT, McMahon A, McNamara JR, Hartigan SD, Griffin M, Buggy DJ. Comparing erector spinae plane block with serratus anterior plane block for minimally invasive thoracic surgery: a randomised clinical trial. Br J Anaesth. 2020 Nov;125(5):802-810. doi: 10.1016/j.bja.2020.06.020. Epub 2020 Jul 11.

    PMID: 32660716RESULT

Study Officials

  • Dr. Hamood Ur Rehman, MBBS

    Shaukat Khanam Memorial Cancer Hospital & Research Centre Lahore

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
Masking Details
Interventional regional blocks were provided by consultants with privileges of nerve blocks. Patients, investigators and nursing staff accessing pain score were blinded from the intervention.
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: double blinded randomized control trial
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 15, 2026

First Posted

January 23, 2026

Study Start

November 7, 2024

Primary Completion

August 11, 2025

Study Completion

August 27, 2025

Last Updated

January 23, 2026

Record last verified: 2026-01

Data Sharing

IPD Sharing
Will not share

Locations

PA(1)