NCT07358338

Brief Summary

The goal of this clinical trial is to improve comprehensive rehabilitation programs for elderly patients with chronic cerebral ischemia by incorporating training methods with biofeedback for postural control training. The main objectives of the study are as follows: To evaluate the effectiveness of incorporating stabilometric training with biofeedback using the Huber system (LPG Systems, France) and treadmill-based biofeedback training using the C-Mill system (Physiomed Elektromedizin AG, Germany) into comprehensive rehabilitation programs, with respect to postural and cognitive functions in elderly patients with chronic cerebral ischemia. To conduct a comparative analysis of the effectiveness of training programs performed using the Huber (LPG Systems, France) and C-Mill (Physiomed Elektromedizin AG, Germany) biofeedback systems, based on outcomes related to gait pattern recovery, postural parameters, and cognitive performance. The investigators will compare training sessions using the Huber and C-Mill biofeedback systems with a control group (patients receiving conventional therapeutic exercise) in order to determine whether these devices are effective in improving postural control and reducing the risk of falls in patients with chronic cerebral ischemia. Participants are required to: Complete a course consisting of 8 procedures, performed once daily. Report any adverse events occurring during or after the procedures, should they arise.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
120

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jun 2025

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2025

Completed
7 months until next milestone

First Submitted

Initial submission to the registry

December 25, 2025

Completed
28 days until next milestone

First Posted

Study publicly available on registry

January 22, 2026

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 6, 2026

Completed
24 days until next milestone

Study Completion

Last participant's last visit for all outcomes

April 30, 2026

Completed
Last Updated

May 5, 2026

Status Verified

May 1, 2026

Enrollment Period

10 months

First QC Date

December 25, 2025

Last Update Submit

May 3, 2026

Conditions

Outcome Measures

Primary Outcomes (4)

  • The risk of falls was reduced more in groups using biofeedback equipment

    Fall risk assessment using the Morse fall scale before and after the rehabilitation course (min 0, max 125, higher values on the scale indicate a worse outcome)

    10 days

  • The risk of falls was reduced more in groups using biofeedback equipment

    Fall risk assessment using the Get-Up-and-Go test before and after the rehabilitation course (Taking more than 14 seconds to complete the test indicates a high risk of falls)

    10 days

  • The risk of falls was reduced more in groups using biofeedback equipment

    Fall risk assessment using the gait speed before and after the rehabilitation course (a walking speed of more than 1 km/h indicates a high risk of falls)

    10 days

  • Static balance will improve more in the group training on the "Huber", and dynamic balance in the group training on the treadmill "Cmill"

    Evaluation based on the following stabilometric indicators: length and area of the statokinesiogram, average speed of oscillations of the body's center of pressure, indicators of the static and dynamic balance tests TUG, Romberg test with open and closed eyes, indicators of the dynamic walking stereotype (walking speed, step length, step variability)

    10 days

Secondary Outcomes (2)

  • Improving cognitive functions

    10 days

  • Improving the quality of life

    10 days

Study Arms (3)

training on the "Huber" (LPG-Systems, France)

EXPERIMENTAL

A course of treatments on the Huber stabilization trainer (LPG-Systems, France); a course of therapeutic exercises consisting of general strengthening exercises, as well as exercises aimed at improving balance and coordination; a course of massage of the cervical and shoulder area using a relaxing technique; a course of magnetic therapy (as indicated).

Device: "Huber" (LPG-Systems, France)

treadmill training on the "C-mill" (Physiomed Elektromedizin AG, Germany)

EXPERIMENTAL

A course of treatments using a C-mill biofeedback video reconstruction treadmill (Physiomed Elektromedizin AG, Germany); a course of therapeutic exercises consisting of general strengthening exercises, as well as exercises aimed at improving balance and coordination; a course of massage of the cervical and shoulder area using a relaxing technique; a course of magnetic therapy (as indicated).

Device: "C-mill" (Physiomed Elektromedizin AG, Germany)

Control group

ACTIVE COMPARATOR

A course of therapeutic exercises consisting of general strengthening exercises, as well as exercises aimed at improving balance and coordination; a course of massage of the cervical and shoulder area using a relaxing technique; a course of magnetic therapy (as indicated).

Other: Physical therapy

Interventions

Procedures on the Huber stabilization trainer (LPG-Systems, France) include a 5-minute warm-up, followed by an individual selection of 3 tasks from the "Balance and Posture" program and 2 tasks from the "Resistance" program from levels 1 to 5.

training on the "Huber" (LPG-Systems, France)

The procedures on the C-mill biofeedback video reconstruction track (Physiomed Elektromedizin AG, Germany) include a warm-up (3 minutes of normal walking), followed by blocks of tasks of 2-4 minutes each: "Slalom", "Tandem", "Obstacles", "Random Marks", "Speed Change", and ending with a cool-down (3 minutes of normal walking).

treadmill training on the "C-mill" (Physiomed Elektromedizin AG, Germany)

The therapeutic exercise program consists of complex coordination exercises in various starting positions, including with objects. Each session will include a 5-minute warm-up, including breathing exercises and active joint exercises, followed by a 15-minute main block of exercises, and concludes with a 3-4-minute cool-down with stretching exercises for the back and lower extremities.

Control group

Eligibility Criteria

Age65 Years - 98 Years
Sexall
Healthy VolunteersNo
Age GroupsOlder Adult (65+)

You may qualify if:

  • Elderly people aged 65 years and older, with a diagnosis of "Chronic cerebral ischemia" (according to the ICD-10 classification - I67.8 Other specified cerebral vascular lesions), atherosclerotic/hypertensive/mixed genesis (E.I. Gusev et al. 2022), clinical stage 1 or 2 according to the guidelines of the Research Institute of Neurology of the Russian Academy of Medical Sciences (2001) with neuroimaging-confirmed structural damage to the brain (stage 1 according to O.S. Levin (2006)
  • Signed voluntary consent to participate in the study.

You may not qualify if:

  • Age under 65, age over 98
  • Chronic diseases in the decompensation stage
  • Severe cognitive impairment
  • History of acute cerebrovascular accident
  • Presence of hemodynamically significant stenosis of the main cerebral arteries
  • Uncontrolled arterial hypertension
  • Neurodegenerative diseases
  • Dysmetabolic encephalopathy
  • History of traumatic brain injury
  • Condition after endoprosthetics of large joints
  • Severe sarcopenia
  • Oncological diseases in the progression stage
  • Lack of informed consent of the patient for the conduct of the study and access to information.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

MEDSI Clinic

Moscow, 143442, Russia

Location

Related Links

MeSH Terms

Conditions

Cerebrovascular DisordersGait Disorders, Neurologic

Interventions

Physical Therapy Modalities

Condition Hierarchy (Ancestors)

Brain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular DiseasesNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

TherapeuticsRehabilitation

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
physiotherapist

Study Record Dates

First Submitted

December 25, 2025

First Posted

January 22, 2026

Study Start

June 1, 2025

Primary Completion

April 6, 2026

Study Completion

April 30, 2026

Last Updated

May 5, 2026

Record last verified: 2026-05

Data Sharing

IPD Sharing
Will not share

Locations