Impact of Sleep Related Breathing Disorders on Outcomes of Acute Pulmonary Embolism

NCT07356908 | Completed DMC

• 2 other identifiers: fac medfaculty of medicin
• Study Type: observational
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

This study aimsto compare short-termclinical outcomesand one-year recurrence rates in patients with acute pulmonary embolism with versus without sleep-disordered breathing, recruited from Alexandria MainUniversityHospital.

Conditions

Pulmonary Embolism; Sleep Apnea Syndrome (OSAS)

Keywords

pulmonary embolism; sleep apnea

Outcome Measures

Primary Outcomes (2)

• Pulmonary embolism recurrence

  ocuurence of pulmonary embolism during the follow up period confirmed by CTPA

  12 months

• Recurrence of Pulmonary Embolism

  occurence of objectively confirmed pulmonary embolism during the one t=year follow up period confirmed by CTPA

  ONE YEAR

Interventions

polysomnography DIAGNOSTIC_TEST

This prospective observational study will include consecutive adult patients admitted to the Chest Diseases Department and related units at Alexandria Main University Hospital (AMUH) with a diagnosis of acute pulmonary embolism confirmed by CTPA

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

adult patients more than 18 years diagnosed with pulmonary embolism managed and followed up at the chest diseases department

You may qualify if:

• Age≥18years.
• Objectively confirmed acute pulmonary embolism by computed tomography pulmonary angiography (CTPA).
• Hemodynamically stable or clinically stabilized within 72 hours of admission. .Ability to provide informed consent.

You may not qualify if:

• Known central sleep apnea without obstructive features. .Inabilityto undergo sleep study evaluation.
• Pregnancy

Sponsors & Collaborators

• Alexandria University: lead
• University of Alexandria: collaborator

Study Sites (1)

Faculty of Medicine

Alexandria, Egypt, 11511, Egypt

Location

Related Links

• Alonso-Fernández A, de la Peña M, Romero D, Piérola J, Carrera M, Barceló A, Soriano JB, García Suquia A, Fernández-Capitán C, Lorenzo A, García-Río F. Association between obstructive sleep apnea and pulmonary embolism. Mayo Clin Proc. 2013 Jun;88(6):579

MeSH Terms

Conditions

Pulmonary Embolism; Sleep Apnea Syndromes; Sleep Apnea, Obstructive

Interventions

Polysomnography

Condition Hierarchy (Ancestors)

Lung Diseases; Respiratory Tract Diseases; Embolism; Embolism and Thrombosis; Vascular Diseases; Cardiovascular Diseases; Apnea; Respiration Disorders; Sleep Disorders, Intrinsic; Dyssomnias; Sleep Wake Disorders; Nervous System Diseases

Intervention Hierarchy (Ancestors)

Monitoring, Physiologic; Diagnostic Techniques and Procedures; Diagnosis

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 13, 2026
• First Posted: January 21, 2026
• Study Start: January 1, 2025
• Primary Completion: January 1, 2026
• Study Completion: January 1, 2026
• Last Updated: January 21, 2026

Record last verified: 2025-01

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)