Process-Based Approach Case Series For Anxiety Problems

NCT07352592 | Recruiting

• 2 other identifiers: IRB-300015520No funding
• Study Type: interventional
• Target: 10
• Locations: 1 country
• Sites: 1

Brief Summary

A case series of PBA intervention for anxiety problems.

Conditions

Anxiety

Keywords

PBT; PBA; Process-Based Approach; Process-Based Cognitive Behavioral Therapy; Anxiety

Outcome Measures

Primary Outcomes (2)

• Generalized Anxiety Disorder-7

  Anxiety scale

  From enrollment to the end of treatment, up to 25 weeks.

• Beck Anxiety Inventory

  Anxiety Measure

  From enrollment to the end of treatment, up to 25 weeks.

Secondary Outcomes (5)

• Patient Health Questionnaire-9

  From enrollment to the end of treatment, up to 25 weeks.

• Experiential Avoidance Rating Scale

  From enrollment to the end of treatment, up to 25 weeks.

• Quality of Life Scale

  From enrollment to the end of treatment, up to 25 weeks.

• Big Five Inventory

  From enrollment to the end of treatment, up to 25 weeks.

• PSY-Flex

  From enrollment to the end of treatment, up to 25 weeks.

Other Outcomes (1)

• Process-based assessment tool

  Five times a day for two weeks prior to intervention

Study Arms (1)

Process-based approach

EXPERIMENTAL

PBA therapy

Behavioral: Process-Based Approach

Interventions

Process-Based Approach BEHAVIORAL

Process-Based Approaches (PBA) were developed to improve psychotherapy outcomes. Early writings referred to PBA as process-based therapy or process-based cognitive behavioral therapy. The current nomenclature was adopted to distinguish PBA as a unifying approach that incrementally builds on clinical psychological science rather than a manualized treatment protocol. PBA provides a framework for flexibly applying evidence-based techniques from multiple therapeutic traditions to target hypothesized psychological processes that give rise to individual patient presentations. Each patient is conceptualized independently, and intervention structure may vary substantially based on need, while retaining empirically supported tools. This contrasts with disorder-specific treatment manuals, which assume homogeneity despite substantial variability in underlying processes (e.g., anxiety).

Also known as: PBT

Process-based approach

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Score on GAD-7 \>10 at baseline
• Access to mobile device

You may not qualify if:

• Current psychotherapy treatment
• Current/past severe psychopathology (e.g., history of psychosis, suicide attempt or self-injury within the past 12 months, narcotics use within the past 3 months)

Sponsors & Collaborators

• University of Alabama at Birmingham: lead

Study Sites (1)

University of Alabama at Birmingham Dr. Borgogna's lab

Birmingham, Alabama, 35233, United States

RECRUITING

MeSH Terms

Conditions

Anxiety Disorders

Condition Hierarchy (Ancestors)

Mental Disorders

Study Officials

• Nicholas C Borgogna, PhD

  University of Alabama at Birmingham

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Damion D Whittinton, MS

CONTACT

(205) 934-3850; whitdrew@uab.edu

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: January 9, 2026
• First Posted: January 20, 2026
• Study Start: June 1, 2026
• Primary Completion (Estimated): December 31, 2029
• Study Completion (Estimated): December 31, 2030
• Last Updated: June 12, 2026

Record last verified: 2026-06

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, ICF, ANALYTIC CODE
• Time Frame: 2027-2030
• Access Criteria: PhD-level researchers associated with academic institutions will have access to de-identified spreadsheets and code.

Locations

US (1)