NCT07352124

Brief Summary

This study aimed to evaluate the effects of daily rosemary infusion consumption on blood pressure and lipid profile in patients with mild hypertension, stratified by triglyceride status. This 6-week open-label interventional study enrolled 47 patients with mild hypertension (systolic BP 140-159 mmHg and/or diastolic BP 90-99 mmHg). Participants were stratified into two groups: normal triglycerides, TG \<1.7 mmol/L, n=22 and high triglycerides, TG ≥1.7 mmol/L, n=25. Blood pressure was assessed using 24-hour ambulatory monitoring (Holter) at baseline and day 45. Comprehensive biochemical analysis included lipid profile, hepatic and renal function markers, and inflammatory parameters.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
47

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Sep 2024

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2024

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2025

Completed
10 months until next milestone

First Submitted

Initial submission to the registry

January 11, 2026

Completed
9 days until next milestone

First Posted

Study publicly available on registry

January 20, 2026

Completed
Last Updated

January 20, 2026

Status Verified

January 1, 2026

Enrollment Period

7 months

First QC Date

January 11, 2026

Last Update Submit

January 11, 2026

Conditions

Hypertension With Hypertriglyceridemia

Keywords

Rosemary infusion, hypertension , Hypertriglyceridemia

Outcome Measures

Primary Outcomes (2)

  • Blood pressure measurement

    45 days

  • Evolution of serum triglycerides

    45 days

Secondary Outcomes (2)

  • Cardiovascular disease risk assessment

    45 days

  • Atherogenic Index of Plasma

    45 days

Study Arms (2)

Groupe triglycérides normaux TG < 1,7 mmol/L n = 22

EXPERIMENTAL
Dietary Supplement: Rosemary infusion

TG ≥ 1,7 mmol/L n = 25

EXPERIMENTAL
Dietary Supplement: rosemary infusion

Interventions

rosemary infusionDIETARY_SUPPLEMENT

Rosemary infusion 100 ml during 45 days

Groupe triglycérides normaux TG < 1,7 mmol/L n = 22

Eligibility Criteria

Age18 Years - 70 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Sassi

Sousse, 4023, Tunisia

Location

MeSH Terms

Conditions

HypertensionHypertriglyceridemia

Condition Hierarchy (Ancestors)

Vascular DiseasesCardiovascular DiseasesHyperlipidemiasDyslipidemiasLipid Metabolism DisordersMetabolic DiseasesNutritional and Metabolic Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Laboratory of Cardiopulmonary System Interactions

Study Record Dates

First Submitted

January 11, 2026

First Posted

January 20, 2026

Study Start

September 1, 2024

Primary Completion

April 1, 2025

Study Completion

April 1, 2025

Last Updated

January 20, 2026

Record last verified: 2026-01

Data Sharing

IPD Sharing
Will not share

Locations

TU(1)