The Effect of Scents Applied During Heel Blood Collection on Newborn Crying Duration, Pain, and Physiological Parameters

NCT07350980 | Completed

• 1 other identifier: Oznur T.
• Study Type: interventional
• Target: 120
• Locations: 1 country
• Sites: 1

Brief Summary

One of the most common and painful procedures in newborns is taking a capillary blood sample from the heel. This basic procedure, widely used in early health assessments, particularly in newborn screening tests, can cause mild to moderate pain.While both pharmacological and non-pharmacological approaches are used in pain management in newborns, the primary goal is to minimize and prevent painful stimuli as much as possible. Non-pharmacological methods are preferred in newborn care because they have no side effects, are easy to apply, low-cost, and caregiver-friendly.

Conditions

Neonatal; Pain Management

Keywords

newborn

Outcome Measures

Primary Outcomes (3)

• crying times

  measuring the crying duration with a stopwatch

  Before the procedure, during the procedure, and for a total of 10 minutes after the procedure.

• heart rate

  Measurement with pulse oximeter

  Before the procedure, during the procedure, and for a total of 10 minutes after the procedure.

• Neonatal infant pain scale

  The scale includes f ive behavioral parameters (facial expression, crying, armmovements, leg movements, and state of arousal) and one physiological parameter (breathing patterns). Each behavior is scored 0-1; the crying parameter is scored 0-1-2. The lowest score is 0 and the highest score is 7.

  Before the procedure, during the procedure, and for a total of 10 minutes after the procedure.

Study Arms (3)

intervention group (Lavender)

EXPERIMENTAL

Lavender

Other: oil

intervention group (tangerine)

EXPERIMENTAL

tangerine

Other: oil

Control group

NO INTERVENTION

rutin

Interventions

oil OTHER

experiment

intervention group (Lavender); intervention group (tangerine)

Eligibility Criteria

• Age: 37 Weeks - 42 Weeks
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)

You may qualify if:

• Gestational age between 38-42 weeks,
• APGAR score of 7 or higher at 5 minutes,
• Neither mother nor baby should have used sedatives, tranquilizers, or anticonvulsants in the last 24 hours,
• Heel prick blood should be planned as part of the routine neonatal screening program,
• No blood should be taken from the heel prick for any other reason before the procedure,
• Parents should voluntarily participate in the study.

You may not qualify if:

• Gestational age of 37 weeks or less,
• APGAR score of 6 or lower at 5 minutes,
• Having a diagnosed lung disease,
• Having a history of atopic dermatitis, hypersensitivity, or allergies,
• Parents should not wish to participate in the study.

Sponsors & Collaborators

• Sakarya University: lead

Study Sites (1)

Sakarya University

Sakarya, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Agnosia

Interventions

Oils

Condition Hierarchy (Ancestors)

Perceptual Disorders; Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Lipids

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Model Details: 2 intervention, 1 control

Study Record Dates

• First Submitted: December 28, 2025
• First Posted: January 20, 2026
• Study Start: June 25, 2025
• Primary Completion: September 15, 2025
• Study Completion: October 20, 2025
• Last Updated: January 20, 2026

Record last verified: 2025-12

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)