Predictors of Laparoscopy Conversion in Adhesive Small Bowel Obstruction

NCT07350447 | Not Yet Recruiting

• 1 other identifier: 14071979
• Study Type: observational
• Target: 170
• Locations: 1 country
• Sites: 7

Brief Summary

The goal of this observational study is to reveal predictors of unsuccessfull laparoscopic intervention in adult patients with adhesive small bowel obstruction. The main question it aims to answer is: are there any strong predictors of laparoscopy conversion in patients with small bowel obstruction, caused by intraabdominal adhesions.

Conditions

Adhesive Small Bowel Obstruction

Keywords

Adhesive small bowel obstruction; Ahesiolysis; Laparoscopic adhesiolysis; abdominal adhesions

Outcome Measures

Primary Outcomes (1)

• Rate of succesfull laparoscopic interventions

  The ratio of successful laparoscopic interventions to the total number of operations

  At the discharge from the hospital (assessed up to 10 days)

Secondary Outcomes (7)

• Diameter of intestinal loops

  Perioperative

• Known or suspected complex adhesive process

  Perioperative

• Number of laparotomy operations

  Perioperative

• Ischemia or necrosis of the intestine

  Perioperative

• Obstruction level

  Perioperative

Study Arms (2)

Laparoscopy group

Patients with acute adhesive intestinal obstruction, operated through surgical intervention, that was initiated and completed using endovideosurgical methods.

Procedure: Laparoscopic adhesiolysis

Conversion group

Patients with acute adhesive intestinal obstruction, in whom surgical intervention was initiated by endovideosurgical means, however, during the operation there was a need for laparotomy and the surgical procedure was completed by laparotomy access.

Procedure: Laparotomic adhesiolysis

Interventions

Laparoscopic adhesiolysis PROCEDURE

Dissection of intra-abdominal adhesions performed laparoscopically in accordance with the principles adopted in the medical institution.

Laparoscopy group

Laparotomic adhesiolysis PROCEDURE

Traditional adhesiolysis, performed via laparotomy after unsuccessfull attempt of endovideosurgical approach.

Conversion group

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients, operated in surgical departments of 4 different hospitals in Saint-Petersburg and one hospital in Perm, Kazan and Yekaterinburg respectively.

You may qualify if:

• patients underwent emergency and urgent surgery for acute adhesive intestinal obstruction
• the surgery was performed laparoscopically
• the surgery was initiated laparoscopically and completed via laparotomy

You may not qualify if:

• acute adhesive intestinal obstruction in the hernial sac
• pregnant in the third trimester
• patients with severe cardiovascular or respiratory failure
• patients with hemodynamic shock

Sponsors & Collaborators

• Almazov National Medical Research Centre: lead

Study Sites (7)

Kazan Federal University

Kazan', Russia

Location

City Clinical Hospital No. 4

Perm, Russia

Location

Almazov National Medical Research Centre

Saint Petersburg, Russia

Location

Mariinskaya Hospital

Saint Petersburg, Russia

Location

Saint-Petersburg I.I. Dzhanelidze research institute of emergency medicine

Saint Petersburg, Russia

Location

The City Hospital of the Holy Martyr Elizabeth

Saint Petersburg, Russia

Location

City Clinical Hospital No. 40

Yekaterinburg, Russia

Location

Study Officials

• Pavel А Kotkov, MD

  Almazov National Medical Research Centre

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Pavel A Kotkov, MD

CONTACT

+79062619231; Kotkovdr@mail.ru

Badri V Sigua, MD

CONTACT

dr.sigua@gmail.com

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant professor of the general surgery department

Study Record Dates

• First Submitted: December 23, 2025
• First Posted: January 20, 2026
• Study Start: January 1, 2026
• Primary Completion: April 30, 2026
• Study Completion (Estimated): May 31, 2026
• Last Updated: January 20, 2026

Record last verified: 2026-01

Locations

RU (7)