Trials Sponsors Conditions Drugs Pricing

Conditions

Maxillary Sinus Augmentation Posterior Maxillary Atrophy

Keywords

sinus augmentationSplit-mouth designPlatelet-rich fibrinHistomorphometric analysisDental implantsdemineralized freeze-dried bone allograft

Outcome Measures

Primary Outcomes (1)

Histomorphometric New Bone Formation (%)
The percentage of newly formed bone in biopsy samples obtained from the augmented maxillary sinus, evaluated by histomorphometric analysis.
6 months after lateral maxillary sinus augmentation

Secondary Outcomes (2)

Residual Graft Material (%)
6 months after lateral maxillary sinus augmentation
Connective Tissue (%)
6 months after lateral maxillary sinus augmentation

Study Arms (2)

Non- PRF(DFDBA Alone)

EXPERIMENTAL

Lateral maxillary sinus augmentation performed using demineralized freeze-dried bone allograft (DFDBA) alone.

Procedure: Lateral Maxillary Sinus Augmentation With DFDBA

PRF(DFDBA + PRF)

EXPERIMENTAL

Lateral sinus floor elevation using demineralized freeze-dried bone allograft combined with autologous platelet-rich fibrin.

Procedure: Lateral Maxillary Sinus Augmentation With DFDBA and PRF

Interventions

Lateral Maxillary Sinus Augmentation With DFDBAProcedure

Lateral sinus floor elevation using demineralized freeze-dried bone allograft for bone augmentation prior to implant placement.

Non- PRF(DFDBA Alone)

Lateral Maxillary Sinus Augmentation With DFDBA and PRFProcedure

Lateral sinus floor elevation using demineralized freeze-dried bone allograft combined with autologous platelet-rich fibrin.

Eligibility Criteria

Age18 Years - 70 Years

Sexall

Healthy VolunteersNo

Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

Adults aged 18 to 70 years.
Patients requiring bilateral lateral maxillary sinus augmentation for dental implant placement.

Sponsors & Collaborators

Marmara University
Otherlead

Study Sites (1)

Marmara University

Istanbul, Maltepe, 34854, Turkey (Türkiye)

MeSH Terms

Interventions

Prolactin-Releasing Hormone

Intervention Hierarchy (Ancestors)

Hypothalamic HormonesPeptide HormonesHormonesHormones, Hormone Substitutes, and Hormone AntagonistsNeuropeptidesPeptidesAmino Acids, Peptides, and ProteinsNerve Tissue ProteinsProteins

Enrollment

21 participants (actual enrollment reported by the registry).

Study Design

Study Type: interventional
Phase: not applicable
Allocation: RANDOMIZED
Masking: SINGLE
Who Masked: OUTCOMES ASSESSOR
Masking Details: Histological and histomorphometric analyses were performed by a blinded examiner who was unaware of the intervention allocation.
Purpose: TREATMENT
Intervention Model: CROSSOVER
Sponsor Type: OTHER
Responsible Party: PRINCIPAL INVESTIGATOR
PI Title: Research Assistant

Study Record Dates

First Submitted

January 9, 2026

First Posted

January 16, 2026

Histologic and Histomorphometric Evaluation of Lateral Maxillary Sinus Augmentation With or Without Platelet-Rich Fibrin

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (2)

Study Arms (2)

Non- PRF(DFDBA Alone)

PRF(DFDBA + PRF)

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Interventions

Intervention Hierarchy (Ancestors)

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (2)

Study Arms (2)

Non- PRF(DFDBA Alone)

PRF(DFDBA + PRF)

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Interventions

Intervention Hierarchy (Ancestors)

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations