Lumbar-Sacral Plexus Block vs Fascia Iliaca Block Plus Low-Dose Spinal Anesthesia for Femoral Neck Fracture Surgery

NCT07346885 | Active Not Recruiting

• 1 other identifier: BursaYIEAH-2024 TBEK 2025/12-1
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

Femoral neck fracture surgery in elderly patients is frequently complicated by intraoperative hypotension and inadequate postoperative analgesia. Regional anesthesia techniques are increasingly preferred to reduce hemodynamic instability and improve pain control. This prospective observational study aims to compare the efficacy of lumbar and sacral plexus block with fascia iliaca block combined with low-dose spinal anesthesia in terms of severe intraoperative hypotension and postoperative analgesic outcomes in patients undergoing surgery for femoral neck fracture.

Conditions

Femoral Neck Fractures; Nerve Block

Outcome Measures

Primary Outcomes (1)

• Incidence of Severe Intraoperative Hypotension

  Severe hypotension defined as mean arterial pressure (MAP) \< 65 mmHg lasting longer than 12 minutes during surgery

  Intraoperative period

Secondary Outcomes (6)

• intraoperative haemodynamic parameters

  intraoperative 2 hours

• Total Intraoperative Sedative and Analgesic Drug Consumption

  intraoperative 2 hours

• Estimated Intraoperative Blood Loss (mL)

  intraoperative 2 hours

• Postoperative Pain Intensity Assessed by the Numeric Rating Scale (NRS)

  postoperative 24 hour

• Intraoperative Vasopressor Consumption

  Intraoperative period

Study Arms (2)

Lumbar and Sacral Plexus Block Group

ACTIVE COMPARATOR

Patients will receive combined lumbar and sacral plexus blocks as the primary regional anesthesia technique for femoral neck fracture surgery, performed by the attending anesthesiologist according to institutional practice.

Procedure: Lumbar and Sacral Plexus Block

Fascia Iliaca Block Combined with Low-Dose Spinal Anesthesia Group

ACTIVE COMPARATOR

Patients will receive low-dose spinal anesthesia combined with a supra-inguinal fascia iliaca block for surgical anesthesia and postoperative analgesia.

Procedure: Fascia Iliaca Block Combined with Low-Dose Spinal Anesthesia

Interventions

Fascia Iliaca Block Combined with Low-Dose Spinal Anesthesia PROCEDURE

Spinal anesthesia will be administered using a 25-gauge Quincke needle. After positioning the patient on the side to be operated on in a lateral position, hypobaric spinal anesthesia will be administered through an appropriate (L3-4 or L4-5) with 1.5 cc of local anesthetic mixture. Before receiving spinal anesthesia, patients will undergo a supra-inguinal fascia iliaca block with 20 to 30 milliliters of 0.25% local anesthetic (bupivacaine).

Fascia Iliaca Block Combined with Low-Dose Spinal Anesthesia Group

Lumbar and Sacral Plexus Block PROCEDURE

For lumbar and sacral plexus blocks, a 10-15 cm ultrasound-visible peripheral nerve block needle and a nerve stimulator will be used. For lumbar plexus shamrock imaging and sacral plexus blocks, parasacral imaging will be used. 0.5% bupivacaine will be used as the local anesthetic.

Lumbar and Sacral Plexus Block Group

Eligibility Criteria

• Age: 18 Years - 90 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• \>18 years and \<90 years
• American Society of Anesthesiologists score between I and IV
• Patients who will undergo femoral neck fracture surgery

You may not qualify if:

• Previous local anesthetic allergy
• Those with bleeding diathesis disorder
• Having a mental disorder
• Those who are allergic to the drugs used
• Patients who did not consent to participate in the study
• Presence of infection in the block area
• Body mass index \>30
• Preoperative or intraoperative general anesthesia
• Patients for whom consent cannot be obtained
• Pregnant patients

Sponsors & Collaborators

• Bursa Yuksek Ihtisas Training and Research Hospital: lead

Study Sites (1)

University of Health Sciences,,Bursa Yuksek Ihtisas Training and Research Hospital,

Bursa, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Femoral Neck Fractures

Interventions

Anesthesia, Spinal

Condition Hierarchy (Ancestors)

Hip Fractures; Femoral Fractures; Fractures, Bone; Wounds and Injuries; Hip Injuries; Leg Injuries

Intervention Hierarchy (Ancestors)

Anesthesia, Conduction; Anesthesia; Anesthesia and Analgesia

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: December 29, 2025
• First Posted: January 16, 2026
• Study Start: December 30, 2025
• Primary Completion (Estimated): July 1, 2026
• Study Completion (Estimated): August 1, 2026
• Last Updated: January 16, 2026

Record last verified: 2026-01

Locations

TU (1)