Investigating the Correlation Between Functional Constipation and Sacroiliac Joint Disorders

NCT07344571 | Active Not Recruiting DMC

• 1 other identifier: 2517
• Study Type: observational
• Target: 200
• Locations: 1 country
• Sites: 1

Brief Summary

Constipation is a common gastrointestinal issue affecting individuals worldwide. Interferential therapy, a form of electrotherapy, has been suggested to have potential benefits in improving gastrointestinal motility and relieving constipation symptoms. Introducing of a new method like electronic cupping therapy with interferential therapy may optimize the therapeutic outcomes by potentially increasing bowel movements and improving overall gastrointestinal function.

Conditions

Constipation

Keywords

constipation; sacroiliac joint disorders

Outcome Measures

Primary Outcomes (3)

• Distraction Test (SI Joint Gapping)

  Position of patient: Supine. force: posterior-lateral force to both ASISs at same time results: pain in SI region

  6 months

• Thigh Thrust Test

  Position of patient: Supine, hip and knee of affected side flexed 90°. force: Stabilize opposite ASIS, apply posterior force through femur. result: Focal SI pain.

  6 months

• Sacral Thrust Test

  Position of patient: Prone. force: Apply an anterior shear force to sacrum (over S2). result: Reproduction of pain in SI region.

  6 months

Study Arms (2)

group A: Patients with constipation

Both the rectum and the sacroiliac joint share innervation from sacral spinal segments S2-S4. Neural signals from the rectum can influence SI joint sensory nerves via viscerosomatic and somatovisceral reflex arcs. This means chronic constipation may both result from and contribute to SI joint dysfunction.

group B: Patients without constipation

Accumulated stool in the rectum and sigmoid colon can physically press on pelvic structures, stretching ligaments and tensioning muscles around the SI joint. This may trigger or mimic SI joint dysfunction.

Eligibility Criteria

• Age: 25 Years - 60 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

male and female participant

You may qualify if:

• history of Chronic Constipation (CC), as defined by either experiencing two or fewer Complete Spontaneous Bowel Movements (CSBMs) per week for a minimum of 6 consecutive months before the screening visit
• Reporting a sensation of incomplete evacuation or straining during at least a quarter of their bowel movements (according to the generally accepted definition of constipation).
• Patients must have had CC persisting for more than 6 months, failed to respond to or be intolerant of medical treatment for at least 3 months
• Not having functional constipation

You may not qualify if:

• \- pregnant or lactating women
• Chronic Constipation (CC) resulting from anorectal malformations such as colorectal or anal organic lesions, pelvic floor disorders requiring surgical intervention as determined by the investigator (such as rectal prolapse, rectocele, or enterocele)
• presence of implanted electronic devices like cardiac pacemakers, defibrillators, cardiac pumps, or spinal stimulators
• CC attributable to medications or neurologic, endocrine, or metabolic conditions
• prior history of partial colectomy; conditions like megacolon, megarectum, or colonic inertia
• skin abnormalities that hinder the placement of electrodes
• women lacking adequate contraception (hormonal or intrauterine device).

Sponsors & Collaborators

• Middle East University: lead

Study Sites (1)

Bassam Ahmed Nabil

October City, Giza Governorate, 6892, Egypt

Location

MeSH Terms

Conditions

Constipation

Condition Hierarchy (Ancestors)

Signs and Symptoms, Digestive; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: associate professor

Study Record Dates

• First Submitted: January 1, 2026
• First Posted: January 15, 2026
• Study Start: April 15, 2023
• Primary Completion (Estimated): September 10, 2026
• Study Completion (Estimated): September 10, 2026
• Last Updated: January 15, 2026

Record last verified: 2026-01

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)