Long COVID Diagnostic Reactivity Assesment Test

NCT07343856 | Enrolling By Invitation

• 1 other identifier: 9/36-2216
• Study Type: interventional
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

This study is a diagnostic clinical investigation designed to evaluate bioelectrical response patterns assessed by electro-acupuncture-based medicament testing. The method is used to identify individual bioelectrical reactivity associated with the presence and persistence of pathological factors and to assess patient-specific responses to tested medicinal substances. The study involves a single-session, non-invasive diagnostic procedure without administration of pharmacological treatment. The primary objective is the methodological evaluation of the diagnostic approach and the characterization of the detected bioelectrical response patterns in the studied population.

Conditions

Long COVID; Post-Acute Sequelae of SARS-CoV-2 Infection

Keywords

Long COVID; Post-acute sequelae of SARS-CoV-2 infection; Bioelectrical assessment; Electroacupuncture diagnostics; Medicament testing; Autonomic dysregulation; Chronic viral persistence; Non-invasive diagnostics

Outcome Measures

Primary Outcomes (1)

• Number of Participants With Bioelectrical Response Patterns Consistent With Viral Persistence

  Non-invasive diagnostic assessment using electroacupuncture-based medicament testing to identify bioelectrical response patterns consistent with viral antigen persistence in participants with post-viral conditions.

  At enrollment (single diagnostic session)

Secondary Outcomes (1)

• Distribution of Bioelectrical Reactivity Patterns During Medicament Testing

  Baseline(Day 1)

Study Arms (1)

Diagnostic Assesment Arm

EXPERIMENTAL

This single-arm study includes participants undergoing a non-invasive electrodiagnostic assessment to evaluate bioelectrical response patterns associated with viral antigen persistence. No therapeutic intervention is administered.

Diagnostic Test: Electrodiagnostic Bioelectrical Assessment

Interventions

Electrodiagnostic Bioelectrical Assessment DIAGNOSTIC_TEST

A non-invasive diagnostic procedure performed during a single session to assess bioelectrical response patterns associated with viral antigen persistence. Measurements are obtained using standardized bioelectrical assessment techniques without administration of any therapeutic agents or interventions.

Diagnostic Assesment Arm

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age 18 years or older
• History of confirmed SARS-CoV-2 infection
• Persistent symptoms consistent with Long COVID lasting ≥12 weeks after acute infection
• Ability to provide informed consent
• Willingness to undergo non-invasive bioelectrical diagnostic assessment

You may not qualify if:

• Acute infectious disease at the time of enrollment
• Severe uncontrolled medical or psychiatric conditions that may interfere with diagnostic assessment
• Implanted electronic medical devices (e.g., pacemaker)
• Pregnancy or breastfeeding
• Inability to comply with study procedures

Sponsors & Collaborators

• Oncology Center,Ministry Of Heath,Uzbekistan: lead

Study Sites (1)

Research Institute of Virology

Tashkent, 100194, Uzbekistan

Location

MeSH Terms

Conditions

Post-Acute COVID-19 Syndrome; Primary Dysautonomias

Condition Hierarchy (Ancestors)

COVID-19; Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases; Post-Infectious Disorders; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Autonomic Nervous System Diseases; Nervous System Diseases

Study Officials

• Naylya Djumaeva, MD,PhD

  Reseacrh Institute of Virology

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: All enrolled participants undergo a single-session diagnostic assessment using medicament testing to evaluate bioelectrical response patterns associated with viral persistence.

Study Record Dates

• First Submitted: December 24, 2025
• First Posted: January 15, 2026
• Study Start: December 5, 2025
• Primary Completion (Estimated): December 30, 2026
• Study Completion (Estimated): January 1, 2027
• Last Updated: January 15, 2026

Record last verified: 2025-12

Locations

UZ (1)