NCT07343167

Brief Summary

Streptococcal anginosus infections (S. constellatus, S. anginosus, and S. intermedius) are characterized by their severity, linked to high mortality and frequent infectious complications. Several studies in the literature highlight this severity, with mortality rates estimated at around 15%. The aim of this research is to identify the factors associated with mortality in Streptococcal anginosus bacteremia.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
400

participants targeted

Target at P75+ for all trials

Timeline
10mo left

Started Sep 2025

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress44%
Sep 2025Mar 2027

Study Start

First participant enrolled

September 8, 2025

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

January 6, 2026

Completed
9 days until next milestone

First Posted

Study publicly available on registry

January 15, 2026

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2027

Expected
7 days until next milestone

Study Completion

Last participant's last visit for all outcomes

March 8, 2027

Last Updated

January 15, 2026

Status Verified

January 1, 2026

Enrollment Period

1.5 years

First QC Date

January 6, 2026

Last Update Submit

January 6, 2026

Conditions

Streptococcal Infections

Keywords

Streptococcal InfectionsStreptococcal Anginosus BacteremiaStreptococcal anginosus infections

Outcome Measures

Primary Outcomes (1)

  • 28-day in-hospital mortality

    28-Day In-Hospital Mortality Following Streptococcal Infection

    28-Day Mortality Following Streptococcal Infection

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Major subject having presented during the study period at least one positive blood culture for Streptococcus anginosus, Streptococcus constellatus, or Streptococcus intermedius in a laboratory at a participating center

You may qualify if:

  • Major subject (≥18 years old)
  • Hospitalized between January 1, 2019, and December 31, 2024, in one of the participating centers
  • Having presented during the study period at least one positive blood culture for Streptococcus anginosus, Streptococcus constellatus, or Streptococcus intermedius in a laboratory at a participating center

You may not qualify if:

  • Refusal to participate in the study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Centre de référence des maladies vectorielles à tiques, CNR Borrelia - CHU de Strasbourg - France

Strasbourg, 67091, France

RECRUITING

MeSH Terms

Conditions

Streptococcal Infections

Condition Hierarchy (Ancestors)

Gram-Positive Bacterial InfectionsBacterial InfectionsBacterial Infections and MycosesInfections

Central Study Contacts

Victor GERBER, MD

CONTACT

33 3 68 85 37 97victor.gerber@chru-strasbourg.fr

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 6, 2026

First Posted

January 15, 2026

Study Start

September 8, 2025

Primary Completion (Estimated)

March 1, 2027

Study Completion (Estimated)

March 8, 2027

Last Updated

January 15, 2026

Record last verified: 2026-01

Locations

FR(1)