Prediabetes in End Stage Renal Disease on Dialysis

NCT07337083 | Completed

• 1 other identifier: Soh-Med-25-4--6PD
• Study Type: observational
• Target: 262
• Locations: 1 country
• Sites: 2

Brief Summary

Prediabetes is a highly prevalent condition, affecting about one-third of adults in the United States Patients with prediabetes have an increased risk for diabetes, with 2% to 10% progressing to diabetes each yea Although prediabetes is frequently considered an intermediary stage in the progression between normoglycemia and diabetes, many individuals may have prediabetes for several years, while some may never progress.

Conditions

Screening; Pre Diabetic; Dialysis Patients; Chronic Renal Failure (CRF)

Outcome Measures

Primary Outcomes (1)

• The prevalence of prediabetes in the End Stage Renal Disease (ESRD) on dialysis cohort.

  "The time frame for measurement of the primary outcome (prevalence of prediabetes) with all diagnostic measurements (Fasting Plasma Glucose mg/dl) performed once per participant at the time of their inclusion in the study."

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study population is defined as adult patients (aged 18 years or older) with End-Stage Renal Disease (ESRD) who are currently on dialysis. This population will be recruited from a single center: Sohag Faculty of Medicine, Sohag University, Egypt.

You may qualify if:

• End stage renal disease on dialysis patients aged ≥ 18 years old.

You may not qualify if:

• Patients previously diagnosed with prediabetes.
• Patients previously diagnosed with diabetes mellitus.
• Acute Medical Status :Hospitalized patients.
• Physiological States: Pregnant females.Lactating females.
• Specific Comorbidities \& Conditions: Polycystic kidney disease.
• New York Heart Association (NYHA) class III or IV heart failure.
• Known liver cirrhosis. or HIV/AIDS.
• Renal cancer.
• Active immunosuppression. or Recent chemotherapy or immunosuppressive therapy.
• History of organ transplantation.

Sponsors & Collaborators

• Sohag University: lead

Study Sites (2)

Faculty of Medicine

Sohag, Egypt, 82525, Egypt

Location

Sohag University .Faculty of Medicine

Sohag, Egypt

Location

MeSH Terms

Conditions

Glucose Intolerance; Kidney Failure, Chronic

Condition Hierarchy (Ancestors)

Hyperglycemia; Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Renal Insufficiency, Chronic; Renal Insufficiency; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: lecturer of internal medicine

Study Record Dates

• First Submitted: January 4, 2026
• First Posted: January 13, 2026
• Study Start: April 13, 2025
• Primary Completion: September 13, 2025
• Study Completion: October 12, 2025
• Last Updated: January 13, 2026

Record last verified: 2025-04

Locations

EG (2)