Case-Specific Health Care Professional Clinical Survey of Liberant™ Thrombectomy System

NCT07335341 | Not Yet Recruiting FDA Device

• 1 other identifier: MDT25034
• Study Type: observational
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of Case-Specific Health Care Professional (HCP) Clinical Survey of Liberant™ Thrombectomy System, also known as the Liberant Clinical Assessment, is to collect first-in-human clinical data to confirm the safety and performance of the Medtronic Liberant™ thrombectomy system when used for the removal of fresh, soft emboli or thrombi from the vessels of the peripheral arterial and venous systems

Conditions

Venous Embolism of Lower Extremities (Diagnosis); Arterial Embolism and Thrombosis; Acute DVT of Lower Extremity; Chronic DVT of Lower Extremity; DVT; Deep Vein Thrombosis Leg; LE ALI; Thrombus in the Peripheral Venous Vasculature; Peripheral Arterial Disease; Acute Limb Ischemia; Lower Extremity Acute Limb Ischemia

Keywords

Thrombus in Peripheral Arterial Systems; Thrombectomy; Thrombosis; Venous Thrombosis; Aspiration Thrombectomy; Percutaneous Mechanical Thrombectomy; Arterial Occlusive Diseases; Vascular Diseases; Peripheral Vascular Diseases; Peripheral Arterial Disease; Mechanical Thrombectomy; Aspiration; Liberant Thrombectomy System; adverse events; Excipio; Thrombus in Peripheral Venous Systems

Outcome Measures

Primary Outcomes (3)

• Rate of Device related Serious Adverse Event at Index procedure

  An Adverse Event that converted to Serious Adverse Event, involving the function of the subject device, or the presence of the device in the body, including events that are directly attributable to the Liberant Thrombectomy System

  Index Procedure

• Rate of technical success at Index procedure

  Technical success: Successful introduction, delivery, aspiration of fresh, soft emboli or thrombi, and retrieval of the Liberant per the Instructions for Use (IFU) during the index procedure

  Index procedure

• Rate of Procedural Success at Index procedure

  Procedure success: Successful removal of fresh, soft emboli or thrombi and restoration of adequate blood flow, inclusive of all endovascular therapies during the index procedure

  Index procedure

Interventions

Liberant Thrombectomy System DEVICE

The Liberant thrombectomy system is indicated for the removal of fresh, soft emboli or thrombi from the vessels of the peripheral arterial and venous systems

Eligibility Criteria

• Age: 22 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The Liberant thrombectomy system is intended for use in adult patients with occluded peripheral arterial and venous vessels.

Patient case selection to be included in the clinical assessment will be specific to Liberant and will be made according to the following criteria: 1. Patient treated is age ≥ 22 years at the time of procedure 2. Use of Liberant in accordance with the device labeling within 72 hours of index procedure

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

• Medtronic Endovascular: lead

Study Sites (1)

Naples Comprehensive Health

Naples, Florida, 34108, United States

Location

MeSH Terms

Conditions

Disease; Thrombosis; Venous Thrombosis; Peripheral Arterial Disease; Arterial Occlusive Diseases; Vascular Diseases; Peripheral Vascular Diseases

Condition Hierarchy (Ancestors)

Pathologic Processes; Pathological Conditions, Signs and Symptoms; Embolism and Thrombosis; Cardiovascular Diseases; Atherosclerosis; Arteriosclerosis

Study Officials

• John R Laird Jr, MD

  Medtronic Endovascular

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Manasa Gudipally

CONTACT

763-514-4000; manasa.gudipally@medtronic.com

Janki Shah

CONTACT

janki.shah@medtronic.com

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: INDUSTRY
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 5, 2026
• First Posted: January 13, 2026
• Study Start: March 1, 2026
• Primary Completion (Estimated): August 1, 2026
• Study Completion (Estimated): August 1, 2026
• Last Updated: March 4, 2026

Record last verified: 2026-02

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)