NCT07333872

Brief Summary

A comparative evaluation for three vital pulp therapy techniques in primary molars using the same material (MTA)

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
96

participants targeted

Target at P50-P75 for not_applicable

Timeline
2mo left

Started Jun 2025

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress89%
Jun 2025Jun 2026

Study Start

First participant enrolled

June 1, 2025

Completed
7 months until next milestone

First Submitted

Initial submission to the registry

January 1, 2026

Completed
11 days until next milestone

First Posted

Study publicly available on registry

January 12, 2026

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 31, 2026

Expected
20 days until next milestone

Study Completion

Last participant's last visit for all outcomes

June 20, 2026

Last Updated

January 13, 2026

Status Verified

May 1, 2025

Enrollment Period

12 months

First QC Date

January 1, 2026

Last Update Submit

January 11, 2026

Conditions

Vital Pulp Therapy in Primary Teeth

Outcome Measures

Primary Outcomes (2)

  • Spontaneous pain

    numeric rating scale (presence or abscence of pain) 0 is best result 10 is the worst

    12 months

  • Radiolucency of the periapical or furcation area

    measuring tool is x-ray

    Follow up for 12 months

Secondary Outcomes (5)

  • Presence or absence of fistula

    12 months

  • Pathological mobility

    12 months

  • Sensitivity on percussion

    12 months

  • Widening of personal ligament space

    12 months

  • Internal or e ternal resorption

    12 months

Study Arms (3)

Direct pulp capping

EXPERIMENTAL

Technique of vital pulp therapy to cap pin point exposure

Procedure: pulp capping with MTA

Partial pulpotomy

EXPERIMENTAL

Technique of vital pulp therapy to cap widened pulp exposure

Procedure: pulp capping with MTA

Pulpotomy

EXPERIMENTAL

Technique of vital pulp therapy of capping radicular pulp after removal of coronal pulp

Procedure: pulp capping with MTA

Interventions

pulp capping with MTAPROCEDURE

Capping of the pulp tissue with a biocompatible material (MTA)

Direct pulp cappingPartial pulpotomyPulpotomy

Eligibility Criteria

Age4 Years - 7 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • articipants were cooperative children (4-7 years) with no systemic diseases or relevant allergies. Eligible teeth were restorable primary second molars with deep carious lesions and a diagnosis of reversible pulpitis,

You may not qualify if:

  • spontaneous pain, edema, fistula, pathological mobility, or percussion sensitivity.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Delta university for science and technology

Gamasa, Dakahlia Governorate, 35516, Egypt

Location

MeSH Terms

Interventions

Dental Pulp CappingPemetrexed

Intervention Hierarchy (Ancestors)

EndodonticsDentistryGuanineHypoxanthinesPurinonesPurinesHeterocyclic Compounds, 2-RingHeterocyclic Compounds, Fused-RingHeterocyclic CompoundsGlutamatesAmino Acids, AcidicAmino AcidsAmino Acids, Peptides, and ProteinsAmino Acids, Dicarboxylic

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 1, 2026

First Posted

January 12, 2026

Study Start

June 1, 2025

Primary Completion (Estimated)

May 31, 2026

Study Completion (Estimated)

June 20, 2026

Last Updated

January 13, 2026

Record last verified: 2025-05

Locations

EG(1)