Impact of Dialysis on Sexuality.

NCT07332949 | Recruiting

• 2 other identifiers: 2025/042025-A02271-48
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

Sexuality is an essential dimension of quality of life and is frequently impaired in patients with end-stage chronic kidney disease undergoing hemodialysis. Sexual dysfunctions-including erectile dysfunction, reduced sexual desire, and difficulties with arousal or orgasm-are highly prevalent in this population. These disorders have multifactorial origins, involving hormonal disturbances, comorbidities, treatment-related side effects, chronic fatigue, and the psychological and relational impact of long-term illness. Despite their frequency, sexual health issues are rarely addressed in routine dialysis care. This is largely due to time constraints during consultations, insufficient training of healthcare professionals, and persistent social and cultural taboos. In addition, the existing scientific literature remains limited, often outdated, and predominantly focused on male patients. Data concerning women, sexual diversity, body image, and couple-related aspects are scarce. Standard kidney disease-specific quality-of-life instruments, such as the KDQOL questionnaire, provide only a minimal assessment of sexuality, with a single item related to sexual desire. The aim of this study is to provide a contemporary and comprehensive assessment of the impact of dialysis on sexual quality of life. By documenting sexual function and sexual complaints in patients undergoing dialysis, this study seeks to improve understanding of patients' experiences and to facilitate communication between patients and healthcare professionals. Ultimately, the findings are intended to support better integration of sexual health into routine nephrology care and to contribute to improved clinical practices in the field of sexual health. This study is designed as a cross-sectional survey conducted among patients undergoing dialysis at the Groupe Hospitalier Privé Ambroise Paré-Hartmann in the Paris area. Eligible patients are informed about the study during a dialysis session by a healthcare professional (dialysis nurse, nephrologist, or physiotherapist specialized in sexology). Participants complete a self-administered questionnaire during their dialysis session, including the Male Sexual Health Questionnaire (MSHQ) for men and the Female Sexual Function Index (FSFI) for women. Additional questions addressing medical history and body image perception are included. The estimated completion time for the questionnaire is approximately 20 minutes.

Conditions

Chronic Kidney Disease Requiring Chronic Dialysis

Keywords

Hemodialysis; Peritoneal dialysis; Sexuality

Outcome Measures

Primary Outcomes (2)

• Sexual quality of life

  The MSHQ questionnaire for men consists of 25 questions, minimum score: 25, maximum score: 125. A higher score on this scale indicates better sexual function.

  At baseline, during a dialysis session

• Sexual quality of life

  The FSFI questionnaire for women consists of 19 questions, minimum score: 2, maximum score: 36. A higher score on this scale indicates better sexual function.

  At baseline, during a dialysis session

Secondary Outcomes (1)

• Body perception

  At baseline, during a dialysis session

Study Arms (1)

Adults treated with chronic dialysis

Other: Questionnaire on sexuality

Interventions

Questionnaire on sexuality OTHER

The patients will receive the following questionnaires to complete during the dialysis session: * MSHQ (Male Sexual Health Questionnaire) for men * FSFI (Female Sexual Function Index) for women Additional questions addressing medical history and body image perception are included.

Adults treated with chronic dialysis

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Adults treated with chronic dialysis (hemodialysis or peritoneal dialysis).

You may qualify if:

• Patient \> 18 years,
• Treated with chronic dialysis (hemodialysis or peritoneal dialysis) for at least 6 months.

You may not qualify if:

• Major cognitive or psychiatric disorders that make understanding or completing the questionnaire difficult.
• General health condition not allowing participation without significant discomfort or excessive fatigue.
• Opposition by the patient.

Sponsors & Collaborators

• CMC Ambroise Paré: lead

Study Sites (1)

Ambroise Paré - Hartmann Private Hospital Group

Neuilly-sur-Seine, Île-de-France Region, 92200, France

RECRUITING

MeSH Terms

Conditions

Sexuality

Condition Hierarchy (Ancestors)

Sexual Behavior; Behavior

Central Study Contacts

Nicolas Benichou, MD

CONTACT

0146415079; nicolas.benichou@clinique-a-pare.fr

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 19, 2025
• First Posted: January 12, 2026
• Study Start: January 30, 2026
• Primary Completion (Estimated): January 30, 2027
• Study Completion (Estimated): January 30, 2027
• Last Updated: February 4, 2026

Record last verified: 2026-02

Locations

FR (1)