NCT07331415

Brief Summary

To evaluate the usefulness of telephone text messages (TTM) in the control of risk factors and in the reduction of events in the first year after an ACS (acute coronary syndrome).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
370

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started May 2019

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2019

Completed
3.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2023

Completed
28 days until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2023

Completed
2.8 years until next milestone

First Submitted

Initial submission to the registry

December 28, 2025

Completed
12 days until next milestone

First Posted

Study publicly available on registry

January 9, 2026

Completed
Last Updated

January 9, 2026

Status Verified

December 1, 2025

Enrollment Period

3.8 years

First QC Date

December 28, 2025

Last Update Submit

December 28, 2025

Conditions

Acute Coronary SyndromeMyocardial InfarctionCardiovascular Diseases

Keywords

Text messagingUsual care

Outcome Measures

Primary Outcomes (1)

  • Composite of cardiac death, myocardial infarction, stroke or new revascularization

    Occurrence of Composite of cardiac death, myocardial infarction, stroke or new revascularization

    12 months

Secondary Outcomes (14)

  • Systolic blood pressure (SBP) mm Hg

    12 months

  • Diastolic blood pressure (DBP) (mm Hg)

    12 months

  • Change in Weight (kilograms)

    12 months

  • Low Density Lipoproteins (LDL) cholesterol (mg/dl)

    12 months

  • High (HDL) cholesterol (mg/dl)

    12 months

  • +9 more secondary outcomes

Study Arms (2)

Text messaging group with usual care

EXPERIMENTAL
Other: Text messaging and Usual Care

Usual Care

ACTIVE COMPARATOR
Behavioral: Usual Care

Interventions

Text messaging and Usual CareOTHER

The patient received a monthly telephone text messages (TTM) for 12 months with the recommendations of the Spanish Society of Cardiology regarding secondary prevention and followed the usual review protocol in a specific ischemic heart disease consultation at 3 and 12 months after discharge.

Text messaging group with usual care
Usual CareBEHAVIORAL

The patient received followed the usual review protocol in a specific ischemic heart disease consultation at 3 and 12 months after discharge.

Usual Care

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients discharged with ACS and without ST elevation.
  • Informed consent signed.

You may not qualify if:

  • Refusal to participate in the study.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hospital Universitario de Cabueñes

Cabueñes, Spain

Location

Related Publications (5)

  • Free C, Phillips G, Galli L, Watson L, Felix L, Edwards P, Patel V, Haines A. The effectiveness of mobile-health technology-based health behaviour change or disease management interventions for health care consumers: a systematic review. PLoS Med. 2013;10(1):e1001362. doi: 10.1371/journal.pmed.1001362. Epub 2013 Jan 15.

    PMID: 23349621BACKGROUND

  • Sharma P APMptm, in fpatat, en/ pwHiRchawirhacsc, 2015). aF.

    BACKGROUND

  • Anglada-Martinez H, Riu-Viladoms G, Martin-Conde M, Rovira-Illamola M, Sotoca-Momblona JM, Codina-Jane C. Does mHealth increase adherence to medication? Results of a systematic review. Int J Clin Pract. 2015 Jan;69(1):9-32. doi: 10.1111/ijcp.12582. Epub 2014 Dec 4.

    PMID: 25472682BACKGROUND

  • Adler AJ, Casas JP, Martin N, Free C, Perel P. Cochrane corner: text messaging to improve adherence to drugs for secondary prevention of cardiovascular disease. Heart. 2018 Nov;104(22):1814-1816. doi: 10.1136/heartjnl-2017-312888. Epub 2018 May 14. No abstract available.

    PMID: 29760242BACKGROUND

  • Senatore FF, Califf RM. Standardized classification and framework for reporting and interpreting medication non-adherence in clinical trials. Eur Heart J. 2019 Jul 1;40(25):2086-2088. doi: 10.1093/eurheartj/ehy759. No abstract available.

    PMID: 30496403BACKGROUND

MeSH Terms

Conditions

Acute Coronary SyndromeMyocardial InfarctionCardiovascular Diseases

Condition Hierarchy (Ancestors)

Myocardial IschemiaHeart DiseasesVascular DiseasesInfarctionIschemiaPathologic ProcessesPathological Conditions, Signs and SymptomsNecrosis

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 28, 2025

First Posted

January 9, 2026

Study Start

May 1, 2019

Primary Completion

February 1, 2023

Study Completion

March 1, 2023

Last Updated

January 9, 2026

Record last verified: 2025-12

Locations

ES(1)