NCT07328269

Brief Summary

The temporomandibular joint dysfunction is the second most common musculoskeletal pain after back pain, causing jaw pain, restricted movement, and joint sounds. NPRS and millimeter ruler will be used for the assessment of patient. This study will compare the effects of Mulligan and Maitland mobilization, commonly used treatment, on pain and Temporomandibular joint mobility through a randomized controlled trial, involving 30 participants divided into two groups for treatment.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Sep 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 5, 2025

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

December 26, 2025

Completed
4 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 30, 2025

Completed
6 days until next milestone

Study Completion

Last participant's last visit for all outcomes

January 5, 2026

Completed
4 days until next milestone

First Posted

Study publicly available on registry

January 9, 2026

Completed
Last Updated

January 9, 2026

Status Verified

December 1, 2025

Enrollment Period

4 months

First QC Date

December 26, 2025

Last Update Submit

December 26, 2025

Conditions

Keywords

HypomobilityMulligan MobilizationMaitland Mobilization

Outcome Measures

Primary Outcomes (2)

  • Pain intensity

    Pain will be measured through Numeric Pain Rating Scale. The scoring for NPRS involves a scale from 0 to 10, where 0 indicates no pain. The interpretation of scores is as follows: 0 to 3 for mild pain, 4 to 6 for moderate pain, and 7 to 10 for severe pain.

    2 weeks

  • Temporomandibular joint Hypomobility

    Mandibular movements were assessed using a millimeter ruler to measure depression (50-60 mm), protrusion (5 mm), and lateral deviation (12-15 mm). Any "click" sounds or deviations during movement were recorded. Jaw movements maintained upper and lower teeth contact.

    2 weeks

Study Arms (2)

Mulligan Mobilization

ACTIVE COMPARATOR

Experimental Group A-Mulligan Mobilization. Myofascial release of temporalis and masseter muscle, Rocabado 6\*6 exercise program.

Procedure: Mulligan Mobilization

Maitland Mobilization

EXPERIMENTAL

Experimental Group B-Maitland Mobilization. Myofascial release of temporalis and masseter muscle. Rocabado 6\*6 exercise program.

Procedure: Maitland Mobilization

Interventions

Both Mulligan and Maitland mobilization techniques with Myofascial release of temporalis and masseter and Rocabado 6\*6 exercise program are applied over a two-week period with six sessions in total, focusing on improving TMJ mobility and reducing pain. Group A Mulligan mobilization emphasizes active patient involvement combined with therapist-applied glides, including lateral, anterior, medial, and distraction glides performed for 5-10 seconds with 3-5 repetitions per session. These techniques enhance mouth opening, lateral deviation, protrusion, and joint space while reducing stiffness and pain. And baseline treatment of myofascial release of temporalis and masseter muscle and Rocabado's 6\*6 exercise program

Mulligan Mobilization

Group B-Maitland mobilization relies on graded oscillatory movements (Grades I-III) for 5-10 seconds with 3-5 oscillations, targeting pain relief and mobility in the pain-free range. Lower grades (I-II) are used for acute pain with gentle oscillations, while higher grades (II-III) provide moderate mobilization to improve protrusion, lateral deviation, and joint capsule mobility. And baseline treatment of myofascial release of temporalis and masseter muscle and Rocabado's 6\*6 exercise program.

Maitland Mobilization

Eligibility Criteria

Age19 Years - 44 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Age 19-44 years.
  • Both Genders (Male and Female).
  • Patients diagnosed with TMJ hypomobility using the Manual Functional Analysis questionnaire based on DC/TMD criteria.
  • Individuals with myofascial pain, scoring above 5 on the NRS and pain upon palpation of at least two of eight masticatory and neck muscles.
  • Subjects with acute TMD and myofascial pain unrelated to active inflammation, infection, or recent trauma for at least six months.

You may not qualify if:

  • Hypermobility of TMJs.
  • Pregnancy.
  • History of rheumatic and inflammatory diseases.
  • A history of temporomandibular disorders treatment within last three months.
  • Acute trauma or injuries of face, head or cervical spine, neurological disorders, taking medication that could affect the musculoskeletal system.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Foundation University College of Physical Therapy

Islamabad, Punjab Province, Pakistan

RECRUITING

MeSH Terms

Conditions

Temporomandibular Joint Disorders

Condition Hierarchy (Ancestors)

Craniomandibular DisordersMandibular DiseasesJaw DiseasesMusculoskeletal DiseasesJoint DiseasesMuscular DiseasesStomatognathic Diseases

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Masking Details
Participant will just have an idea of two interventions not the one given to him/her.
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Participant divided into Two groups Group A recieves Mulligan Mobilization and Group B receives Maitland Mobilization with baseline treatment of myofascial release of temporalis and masseter muscle and Rocabado's 6\*6 exercise program.
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 26, 2025

First Posted

January 9, 2026

Study Start

September 5, 2025

Primary Completion

December 30, 2025

Study Completion

January 5, 2026

Last Updated

January 9, 2026

Record last verified: 2025-12

Locations