Effect of Mental Arithmetic Priming on Gait and Balance in Stroke
MA-Stroke
Mental Calculus Can Enhance Gait Performance in Post-Stroke Patients: A Randomized Controlled Trial
1 other identifier
interventional
17
0 countries
N/A
Brief Summary
This study investigates the effect of cognitive priming through mental arithmetic on functional mobility in post-stroke patients. It hypothesizes that performing mental calculations (addition, subtraction, multiplication) prior to movement stimulates frontoparietal networks, thereby improving gait speed and dynamic balance compared to a passive control condition.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable stroke
Started Feb 2026
Shorter than P25 for not_applicable stroke
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
December 25, 2025
CompletedFirst Posted
Study publicly available on registry
January 8, 2026
CompletedStudy Start
First participant enrolled
February 11, 2026
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 1, 2026
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2026
ExpectedFebruary 12, 2026
February 1, 2026
3 months
December 25, 2025
February 10, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Gait Speed (10mWT)
Assessed using the Ten-Meter Walk Test (10mWT). Participants walk 14 meters; time is recorded for the middle 10 meters to determine steady-state gait speed.
Immediately following the 30-second cognitive stimulus.
Dynamic Balance (TUG)
Assessed using the Timed Up and Go (TUG) test. Time taken to stand from a chair, walk 3 meters, turn, walk back, and sit down.
Immediately following the 30-second cognitive stimulus.
Study Arms (2)
Intervention: Behavioral: Mental Arithmetic
EXPERIMENTALVisual presentation of arithmetic equations (Addition, Subtraction, Multiplication) projected on a screen. Participants must calculate and verbally report the answer within a 10-second window per equation.
Passive Viewing
PLACEBO COMPARATORPassive viewing of a black screen with no cognitive demand.
Interventions
Visual presentation of arithmetic equations (Addition, Subtraction, Multiplication) projected on a screen. Participants must calculate and verbally report the answer within a 10-second window per equation.
Eligibility Criteria
You may qualify if:
- Diagnosis of stroke.
- Mini-Mental State Examination (MMSE) score ≥ 23.
- Ability to walk 10 meters independently (with or without assistive device).
You may not qualify if:
- Hemianopia.
- Wernicke's aphasia or Global aphasia.
- Orthopedic injuries or recent surgeries affecting the lower limbs.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (1)
Khayat J, Champely S, Diab A, Rifai Sarraj A, Fargier P. Effect of mental calculus on the performance of complex movements. Hum Mov Sci. 2019 Aug;66:347-354. doi: 10.1016/j.humov.2019.05.008. Epub 2019 May 28. No abstract available.
PMID: 31146193BACKGROUND
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- PARTICIPANT
- Masking Details
- Single Blind (Participant)
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor
Study Record Dates
First Submitted
December 25, 2025
First Posted
January 8, 2026
Study Start
February 11, 2026
Primary Completion
May 1, 2026
Study Completion (Estimated)
June 1, 2026
Last Updated
February 12, 2026
Record last verified: 2026-02
Data Sharing
- IPD Sharing
- Will share
- Shared Documents
- STUDY PROTOCOL, SAP, ICF
- Time Frame
- Data will be available beginning 6 months and ending 5 years following article publication.
- Access Criteria
- Data will be shared with researchers who provide a methodologically sound proposal to the corresponding author. Proposals should be directed to ahmadrifaisarraj@ul.edu.lb. To gain access, data requestors will need to sign a data access agreement.
Individual participant data (IPD) that underlie the results reported in this article (after de-identification) will be shared. This includes the data used to generate the tables and figures.