NCT07326696

Brief Summary

This study is a randomised controlled trial and the purpose of this study is to determine the effects of thoracic thrust with cervical non-thrust mobilization in mechanical neck pain on components such as pain, thoracic range of motion, kyphotic angle, craniovertebral angle and proprioception.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
46

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jan 2025

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 25, 2025

Completed
11 months until next milestone

First Submitted

Initial submission to the registry

December 26, 2025

Completed
4 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 30, 2025

Completed
9 days until next milestone

First Posted

Study publicly available on registry

January 8, 2026

Completed
7 days until next milestone

Study Completion

Last participant's last visit for all outcomes

January 15, 2026

Completed
Last Updated

January 8, 2026

Status Verified

December 1, 2025

Enrollment Period

11 months

First QC Date

December 26, 2025

Last Update Submit

December 26, 2025

Conditions

Keywords

neck painchronic neck painmechanical neck pain

Outcome Measures

Primary Outcomes (5)

  • Pain Intensity

    Pain will be assessed by Numeric pain scale rating (NPRS).It is numeric 11-point scale, with 0 meaning no pain and 10 being worst pain.

    baseline, 1st and 2nd week

  • Thoracic kyphosis

    Thoracic Kyphosis is measured by Inclinometer. It is measured via summation of angles of two inclinometers, placed on anatomical landmarks (T1-3-12).

    baseline, 1st week and 2nd week

  • Thoracic Range of Motion

    Thoracic ROM (rotation) is measured by Inclinometer. Measured by placing the inclinometer at T1 segment with participant in a lumbar locked position.

    baseline, 1st week, 2nd week

  • Craniovertebral angle

    Craniovertebral angle (CVA)is measured by Goniometer. it is Angle measured between tragus of ear and C7 spinous process.

    baseline,1st week, 2nd week

  • Proprioception

    Proprioception is measured by Joint position sense/ error test. Participant wears a laser mounted headband and performs active neck movements with eyes closed on a target.

    baseline, 1st and 2nd week

Study Arms (2)

Group A; thoracic thrust

EXPERIMENTAL

thoracic thrust in addition to standard treatment

Procedure: Group A:Thoracic thrust

Group B: cervical non-thrust mobilization

ACTIVE COMPARATOR

standard treatment of cervical non-thrust mobilization and home-based therapeutic exercises

Procedure: Group B: Cervical non thrust mobilization

Interventions

Group A will receive manipulation protocol as addition to standard treatment. Manipulation protocol: High velocity, low amplitude as described by Maitland on thoracic hypomobile segments (T1-6) Therapeutic exercise protocol: Cervical and thoracic mobility exercises.

Group A; thoracic thrust

Intervention: Group B will receive mobilization, post-facilitation stretch and exercise protocol. Mobilization protocol: Grade III or IV mobilization as described by Maitland on cervical Hypomobile segments (C2-7) Therapeutic exercise protocol: Cervical and thoracic mobility exercises.

Group B: cervical non-thrust mobilization

Eligibility Criteria

Age20 Years - 40 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Both male and female
  • Age: 20-40 years
  • Numeric pain rating scale (3\<) (13)
  • Neck pain for more than 3 months
  • Cervical hypomobility (C2-C7)
  • Thoracic hypomobility (T1-T6)
  • CranioVertebral Angle \< 48 Degrees

You may not qualify if:

  • Serious pathology (e.g. neoplasm, fracture)
  • History of whiplash injury within the past 6 months
  • Cervical spinal stenosis
  • Radiculopathy
  • Neurological deficit
  • Structural deformities
  • Vertebrobasilar artery insufficiency
  • Pregnancy
  • Prior surgery of cervical or thoracic spine

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Foundation University College of Physical Therapy

Islamabad, Punjab Province, 46000, Pakistan

RECRUITING

MeSH Terms

Conditions

Neck Pain

Condition Hierarchy (Ancestors)

PainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Central Study Contacts

Quratulain Saeed, MS-OMPT

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Masking Details
Participant will be blinded to the allocation of treatement groups
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 26, 2025

First Posted

January 8, 2026

Study Start

January 25, 2025

Primary Completion

December 30, 2025

Study Completion

January 15, 2026

Last Updated

January 8, 2026

Record last verified: 2025-12

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