NCT07323498

Brief Summary

This randomized controlled trial examines whether imagery-based extinction memory updating following a standardized virtual reality (VR) exposure session improves the generalization of exposure effects to novel public speaking contexts. Individuals with elevated public speaking anxiety will complete a single-session VR speech exposure. Participants are randomized to (a) standard mental rehearsal of the exposure experience or (b) mental rehearsal plus guided imagery that updates the extinction memory with novel, non-exposed contexts. Generalization is assessed 7-14 days later using a multi-context behavioral approach test (BAT) in vivo and in VR.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
48

participants targeted

Target at P25-P50 for not_applicable

Timeline
7mo left

Started Nov 2025

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress44%
Nov 2025Dec 2026

Study Start

First participant enrolled

November 26, 2025

Completed
26 days until next milestone

First Submitted

Initial submission to the registry

December 22, 2025

Completed
16 days until next milestone

First Posted

Study publicly available on registry

January 7, 2026

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2026

Expected
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2026

Last Updated

January 9, 2026

Status Verified

January 1, 2026

Enrollment Period

11 months

First QC Date

December 22, 2025

Last Update Submit

January 7, 2026

Conditions

Keywords

virtual reality exposureextinction generalizationfear extinctionexposure therapy

Outcome Measures

Primary Outcomes (2)

  • Public Speaking Anxiety

    Assessed using the Personal Report of Communication Apprehension, Public Speaking Subscale (PRCA-PS). Scores range from 6 to 30, with higher scores associated with higher public speaking anxiety.

    From enrollment to one-week follow-up assessment

  • Subjective Fear During Behavioral Approach Tests

    Self-reported fear during oral presentations, rated on a scale from 0 (no fear) to 100 (severe fear) during each behavioral approach test. Participants were instructed to speak for up to three minutes and could terminate the task at any time. BAT 1: Oral presentation in vivo in front of 3 real listeners BAT 2: Oral presentation in a simulated videoconference with a large audience (30 listeners) BAT 3: Oral presentation in virtual reality (exposure context 1; familiar) BAT 4: Oral presentation in virtual reality (exposure context 2; familiar) BAT 5: Oral presentation in virtual reality (novel context with \~50 virtual listeners) BAT 6: Oral presentation in virtual reality (novel context with \~100 virtual listeners)

    one-week follow-up assessment

Secondary Outcomes (5)

  • Social Anxiety Severity

    From enrollment to one-week follow-up assessment

  • Anticipatory Anxiety Before BATs

    One-week follow-up assessment

  • Behavioral Performance During BATs (Duration of oral presentation during BATs)

    One-week follow-up assessment

  • Valence of Public Speaking

    From enrollment to immediately post-treatment assessment and one-week follow-up assessment

  • Anticipated Fear of Public Speaking

    From enrollment to immediately post-intervention and 1-week follow-up

Study Arms (2)

VR Exposure + Standard Mental Rehearsal

ACTIVE COMPARATOR

Single-session VR exposure intervention: 6 VR speech exposure trials \& Post-exposure standard mental rehearsal

Behavioral: VR ExposureBehavioral: Standard Mental Rehearsal

VR Exposure + Mental Rehearsal With Extinction Memory Updating

EXPERIMENTAL

Single-session VR exposure intervention: 6 VR speech exposure trials \& Post-exposure mental rehearsal with updating the extinction memory with novel, non-exposed contexts

Behavioral: VR ExposureBehavioral: Mental Rehearsal With Extinction Memory Updating

Interventions

VR ExposureBEHAVIORAL

6 VR speech exposure trials (3 min each; topic: "something you are proud of")

VR Exposure + Mental Rehearsal With Extinction Memory UpdatingVR Exposure + Standard Mental Rehearsal

Post-exposure guided imagery: vivid mental rehearsal of the same exposure experience in the same VR contexts (brief, ≤30s each)

VR Exposure + Standard Mental Rehearsal

Post-exposure guided imagery: vivid rehearsal of the exposure experience while updating the extinction memory with novel, non-exposed contexts (e.g., speaking to three real listeners; speaking in a new VR context with a larger audience). Brief, ≤30s each

VR Exposure + Mental Rehearsal With Extinction Memory Updating

Eligibility Criteria

Age18 Years - 70 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • speech anxiety scale score of ≥ 18 on the Personal Report of Communication Apprehension, Public Speaking Subscale (PRCA-PS)
  • Self-report of 18 - 70 years of age

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department of Psychology, Philipps-University of Marburg

Marburg, Hesse, 35037, Germany

RECRUITING

MeSH Terms

Conditions

Glossophobia

Study Officials

  • Christoph Benke, Ph.D.

    Philiips-University of Marburg

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

December 22, 2025

First Posted

January 7, 2026

Study Start

November 26, 2025

Primary Completion (Estimated)

November 1, 2026

Study Completion (Estimated)

December 1, 2026

Last Updated

January 9, 2026

Record last verified: 2026-01

Data Sharing

IPD Sharing
Will not share

Locations