Effects of Exercise With Visual Feedback in Parkinson's Disease

NCT07322939 | Recruiting

• 1 other identifier: HKU/Ph/1
• Study Type: interventional
• Target: 32
• Locations: 1 country
• Sites: 1

Brief Summary

Patients with Parkinson's disease who apply to the Hasan Kalyoncu University Application and Research Center and meet the inclusion criteria will be included in the study. The included participants will be randomly assigned into either the intervention group or the control group using a sealed-envelope method. Both groups will undergo a standard exercise program, consisting of posture, strengthening, and balance training, under the supervision of a physiotherapist for 8 weeks, 3 days per week. In addition to this, the intervention group will receive an additional exercise program incorporating visual feedback using a laser pointer, targeting the trunk and lower extremities, also under the supervision of a physiotherapist for 8 weeks, 3 days per week.

Conditions

Parkinson Disease; Balance Impairment; Exercise Training; Postural Control

Keywords

parkinson disease; balance; postural control; visual feedback; exercise

Outcome Measures

Primary Outcomes (2)

• Center of Pressure Elliptical Area

  Postural control will be assessed using the Gyko wearable device. After the wearable vest is properly fitted, the participant will be asked to maintain balance for 30 seconds under four conditions: firm surface with eyes open, firm surface with eyes closed, soft surface with eyes open, and soft surface with eyes closed. The elliptical area of center of pressure displacement (mm²) obtained from the Gyko system will be recorded for each condition and used as the primary outcome measure.

  up to 8 weeks

• Berg Balance Scale

  The Berg Balance Scale is used to assess functional balance. It evaluates both dynamic and static balance through 14 tasks related to different positions, postural changes, and mobility. Each task is scored between 0 and 4 based on the individual's ability to perform the task independently, for a certain period, or over a specific distance (0: unable to perform, 4: normal performance). The highest possible score on the scale is 56, and a higher score indicates greater independence.

  up to 8 weeks

Secondary Outcomes (11)

• L Test

  up to 8 weeks

• Unified Parkinson's Disease Rating Scale

  up to 8 weeks

• New York Postural Assessment Test

  up to 8 weeks

• Visual Analog Scale

  up to 8 weeks

• Parkinson Fatigue Scale

  up to 8 weeks

Study Arms (2)

standard exercise program

ACTIVE COMPARATOR

Participants in the standard exercise group will receive a physiotherapist-supervised exercise program, performed three times per week for a total duration of eight weeks.

Other: Control Group

standard exercise program and visual feedback-based exercise program

EXPERIMENTAL

Participants in the standard exercise program and visual feedback-based exercise program group will receive a physiotherapist-supervised exercise program, performed three times per week for eight weeks.

Other: Control Group; Other: Visual Feedback Exercise Group

Interventions

Control Group OTHER

The exercises will start with 6-8 repetitions and will increase by 2 repetitions each week. Cervical Region: Cervical rotation, lateral flexion, chin-tuck exercises Upper Extremity: Shoulder joint range of motion exercises with a wand, scapular adduction, shoulder retraction Lower Extremity: Bridge exercise, hip flexion, extension, abduction exercises, knee extension exercises, ankle dorsiflexion - plantar flexion exercises Balance Exercises: Perturbation exercises with eyes open and eyes closed on a hard surface, perturbation exercises with eyes open and eyes closed on a soft surface, maintaining a tandem stance Ambulation: Walking training on a treadmill with a Modified Borg Scale of level 3-4. Walking training will begin with 6 minutes in the first week and will increase by 1 minute each week.

standard exercise program; standard exercise program and visual feedback-based exercise program

Visual Feedback Exercise Group OTHER

The visual feedback exercise will be performed using a wearable laser pointer attached to the trunk and lower extremities, along with a visual tracking screen. The exercise duration is 20 minutes. The laser placed on the trunk will be used in various exercises, including maintaining stability in a seated position, on a Swiss ball, while standing, during different movements, and on various surfaces. Additionally, trunk control exercises will involve rotational, vertical-horizontal, and circular movements. Exercises targeting trunk control in a crawling position will also be included. For the lower extremities, the program will focus on ankle dorsiflexion, hip abduction and extension, and knee extension. All exercises will be progressively individualized on a weekly basis.

standard exercise program and visual feedback-based exercise program

Eligibility Criteria

• Age: 18 Years - 85 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Individuals diagnosed with idiopathic Parkinson's disease
• Disease severity classified as stage 1 to 3 according to the Modified Hoehn and Yahr Scale
• Patients receiving oral antiparkinsonian treatment only
• Presence of musculoskeletal, cardiovascular, or vestibular disorders that may interfere with the completion of the assessments or treatment protocol
• Presence of additional neurological or psychiatric disorders other than Parkinson's disease
• Presence of visual impairment insufficient to perceive visual feedback

Sponsors & Collaborators

• Hasan Kalyoncu University: lead

Study Sites (1)

Hasan Kalyoncu University

Gaziantep, Şahinbey, 27000, Turkey (Türkiye)

RECRUITING

Related Publications (1)

• Kim KI, Im SC, Kim K. Effects of trunk stabilization exercises using laser pointer visual feedback in patients with chronic stroke: A randomized controlled study. Technol Health Care. 2023;31(2):471-483. doi: 10.3233/THC-220100.

  PMID: 36120797 RESULT

MeSH Terms

Conditions

Parkinson Disease; Motor Activity

Interventions

Control Groups

Condition Hierarchy (Ancestors)

Parkinsonian Disorders; Basal Ganglia Diseases; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Movement Disorders; Synucleinopathies; Neurodegenerative Diseases; Behavior

Intervention Hierarchy (Ancestors)

Epidemiologic Research Design; Epidemiologic Methods; Investigative Techniques; Research Design; Methods

Study Officials

• Büşra Akıncı

  Hasan Kalyoncu University

  PRINCIPAL INVESTIGATOR

• Günseli Usgu, Assoc. Prof.

  Hasan Kalyoncu University

  STUDY DIRECTOR

Central Study Contacts

Büşra Akıncı, MSc

CONTACT

+90 (541) 976 55 83; busra.tufekci@hotmail.com

Günseli Usgu, Assoc. Prof.

CONTACT

gunseli.usgu@hku.edu.tr

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, CARE PROVIDER, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: December 5, 2025
• First Posted: January 7, 2026
• Study Start: December 1, 2025
• Primary Completion: April 5, 2026
• Study Completion: May 5, 2026
• Last Updated: January 27, 2026

Record last verified: 2026-01

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)