NCT07322588

Brief Summary

People leaving jail face a very high risk of overdose, especially in the first few weeks after release. Staying on medication for opioid use disorder (MOUD) can greatly reduce this risk, but many people stop treatment during this transition. This study is testing whether a program that offers rewards, called contingency management (CM), can help people stay on MOUD after they return to the community. In this study, people who are taking MOUD in jail can choose to participate. While still incarcerated, they complete one visit where they may receive a small incentive, such as commissary credit or snacks, for enrolling in the CM program. After they leave jail, participants can earn gift cards when they attend their MOUD appointments and counseling sessions. Participants may take part in the study for up to three months after release. During this time, they can earn up to $600 in incentives based on their treatment engagement. Researchers will also ask participants to complete a baseline survey and a survey at 3 months. We will also review medical records to confirm whether they continued their MOUD. The researchers want to learn whether this adapted contingency management program is feasible, acceptable to participants, and helpful for supporting treatment engagement after release from jail. The findings will help determine whether this approach should be tested in a larger study to reduce overdose risk and improve health during the post-release period.

Trial Health

63
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
75

participants targeted

Target at P50-P75 for not_applicable

Timeline
14mo left

Started Jan 2026

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress23%
Jan 2026Jun 2027

First Submitted

Initial submission to the registry

December 1, 2025

Completed
1 month until next milestone

Study Start

First participant enrolled

January 1, 2026

Completed
6 days until next milestone

First Posted

Study publicly available on registry

January 7, 2026

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 30, 2027

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2027

Last Updated

January 7, 2026

Status Verified

December 1, 2025

Enrollment Period

1.5 years

First QC Date

December 1, 2025

Last Update Submit

December 23, 2025

Conditions

Opioid Use Disorder

Keywords

contingency managementopioid use disorderincarcerationreentry

Outcome Measures

Primary Outcomes (1)

  • Number of patients receiving medication for opioid use disorder

    We will assess patient reported receipt of medication for opioid use disorder and also use chart review to determine whether patients are receiving medications and three different time points.

    1, 2, and 3 months

Secondary Outcomes (4)

  • Number of contingency management sessions attended

    3 months

  • Total contingency management rewards earned

    3 months

  • Addiction Severity

    Baseline and 3 months

  • Recovery Capital

    Baseline and 3 months

Study Arms (1)

RISE-CM Intervention

OTHER

All participants are enrolled in the intervention arm.

Other: Reentry Incentives and Support for Engagement with Contingency Management (RISE-CM) Intervention

Interventions

Reentry Incentives and Support for Engagement with Contingency Management (RISE-CM) InterventionOTHER

Participants receive gift card rewards for attending MOUD appointments and counseling appointments after release from incarceration.

RISE-CM Intervention

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Be adults (age ≥18 years) currently incarcerated at Clatsop County Jail
  • Be enrolled in the jail's MOUD program at the time of recruitment
  • Plan to continue MOUD with Clatsop Behavioral Healthcare upon release
  • Speak English and be able to provide informed consent

You may not qualify if:

  • Are unable to provide informed consent due to cognitive impairment or acute psychiatric instability
  • Are scheduled for transfer to a different facility or geographic location that prevents post-release participation

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Clatsop County Corrections

Warrenton, Oregon, 97146, United States

Location

MeSH Terms

Conditions

Opioid-Related Disorders

Interventions

Palliative CareMethods

Condition Hierarchy (Ancestors)

Narcotic-Related DisordersSubstance-Related DisordersChemically-Induced DisordersMental Disorders

Intervention Hierarchy (Ancestors)

Patient CareTherapeuticsHealth ServicesHealth Care Facilities Workforce and ServicesInvestigative Techniques

Study Officials

  • Linda Peng, MD

    Oregon Health and Science University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Carol DeFrancesco Senior Research Associate

CONTACT

5033105036defrance@ohsu.edu

Linda Peng, MD

CONTACT

5034941801pengli@ohsu.edu

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor of Medicine

Study Record Dates

First Submitted

December 1, 2025

First Posted

January 7, 2026

Study Start

January 1, 2026

Primary Completion (Estimated)

June 30, 2027

Study Completion (Estimated)

June 30, 2027

Last Updated

January 7, 2026

Record last verified: 2025-12

Data Sharing

IPD Sharing
Will not share

Locations

US(1)