NCT07319858

Brief Summary

The study aims to investigate the effect of using a multifunctional baby carrier with rocking, safe swaddling, and white noise features on physiological parameters, crying, and sleep status in infants aged 0-3 months who have undergone congenital heart surgery. It is planned to be conducted in a randomized controlled crossover design. Following congenital heart surgery, the use of sedative interventions in the high-stress environment of the intensive care unit has a significant effect on preserving the energy reserves necessary for the infant's growth and development. Using a sensitive and soothing mobile crib to assist in the postoperative care of infants who have undergone congenital heart surgery is a potential opportunity for the infant, nurse, and parent. The combined application of swaddling, sound, and movement reduces the baby's fussiness and has a calming effect on their physiological activation. Infants who underwent heart surgery between 0-3 months and were followed up in a multi-purpose baby carrier (swaddling, white noise, and rocking) compared to infants in the follow-up experimental group, compared to infants in the control group who were only swaddled; Hypothesis 1: The heart rate is lower. Hypothesis 2: Blood pressure is lower. Hypothesis 3: Oxygen saturation levels are higher. Hypothesis 4: Sleep durations are longer. Hypothesis 5: Pain scores are lower.

Trial Health

63
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
52

participants targeted

Target at P25-P50 for not_applicable

Timeline
26mo left

Started Jun 2026

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 20, 2025

Completed
17 days until next milestone

First Posted

Study publicly available on registry

January 6, 2026

Completed
5 months until next milestone

Study Start

First participant enrolled

June 1, 2026

Expected
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2027

1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2028

Last Updated

April 21, 2026

Status Verified

April 1, 2026

Enrollment Period

1.2 years

First QC Date

December 20, 2025

Last Update Submit

April 18, 2026

Conditions

Keywords

nursingpainsleepcongenital heart defectsurgery

Outcome Measures

Primary Outcomes (2)

  • Newborn Pain, Agitation and Sedation Scale (N PASS Scale)

    Term and preterm newborns are used for the purpose of evaluating postoperative pain/agitation and sedation. The total pain score ranges from 0 to +11. A high score indicates significant pain.

    6 hours

  • Sleep-Wake Status Measurement Device (Actigraphy)

    It is used to monitor babies' sleep-wake cycles.

    6 hours

Secondary Outcomes (1)

  • Pediatric Sequential Organ Failure Assessment Score (pSOFA)

    6 hours

Study Arms (2)

Group A

ACTIVE COMPARATOR

Group A (26 babies) : 1. Monitoring in a multifunctional baby carrier for the first 3 hours (experiment) 2. Monitoring in an open incubator for the next 3 hours (control)

Other: Multifunctional Baby Carrier

Group B

ACTIVE COMPARATOR

Group B (26 babies) : 1. Monitoring in an open incubator for the next 3 hours (control) 2. Monitoring in a multifunctional baby carrier for the first 3 hours (experiment)

Other: Multifunctional Baby Carrier

Interventions

The study will be conducted using a randomized controlled crossover design. Infants will be assigned to either group A or group B using a simple randomization method. The infant will be assigned to the control and experimental groups according to the order of initiation within the group to which the infant belongs. Since the study is cross-over in design, infants in both groups (Group A and Group B) will be included in both the experimental group and the control group. Each baby will be monitored for a total of 6 hours. Group A (26 babies): 1. Monitoring in a multifunctional main cradle during the first 3 hours (experiment) 2. Monitoring in an open incubator wrapped for the second 3 hours (control) Group B (26 babies): 1. Monitoring in an open incubator wrapped for the second 3 hours (control) 2. Monitoring in a multifunctional main cradle during the first 3 hours (experiment)

Group AGroup B

Eligibility Criteria

Age1 Day - 3 Months
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • Babies born at 38 weeks or later
  • Babies aged 0 to 3 months after birth
  • No illness other than congenital heart disease
  • Who has undergone surgery for the first time due to congenital heart disease
  • Whose clinical condition is stable (PSOFA score below 8 points)
  • Infants with stable thermoregulation

You may not qualify if:

  • Babies born before 38 weeks of pregnancy
  • Babies older than 3 months
  • The presence of other chromosomal or neurological disorders and syndromes in the infant
  • Those who have undergone two or more surgeries due to congenital heart disease
  • pSOFA score above 8 points

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Health Sciences University Dr. Siyami Ersek Chest, Heart, and Vascular Surgery Education and Research Hospital

Istanbul, Üsküdar, 34668, Turkey (Türkiye)

Location

MeSH Terms

Conditions

PainHeart Defects, Congenital

Condition Hierarchy (Ancestors)

Neurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and SymptomsCardiovascular AbnormalitiesCardiovascular DiseasesHeart DiseasesCongenital AbnormalitiesCongenital, Hereditary, and Neonatal Diseases and Abnormalities

Study Officials

  • Birsen Mutlu, Assc prof

    Istanbul University - Cerrahpasa

    STUDY DIRECTOR

Central Study Contacts

Aynur Baykal, Phd Student

CONTACT

Birsen Mutlu, Assc prof

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
CROSSOVER
Model Details: The study will be conducted using a randomized controlled crossover design. Research groups: 1. Swaddling group (control), 2. Swaddling combined with rocking and white noise feature in a multifunctional primary cradle group. In the crossover design, two groups were defined: Group A and Group B, where interventions were applied in different orders. Infants will be assigned to either group A or group B using a simple randomization method. The infant will be assigned to the control and experimental groups according to the order of initiation within the group to which the infant belongs.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
PHD STUDENT

Study Record Dates

First Submitted

December 20, 2025

First Posted

January 6, 2026

Study Start (Estimated)

June 1, 2026

Primary Completion (Estimated)

August 1, 2027

Study Completion (Estimated)

August 1, 2028

Last Updated

April 21, 2026

Record last verified: 2026-04

Data Sharing

IPD Sharing
Will not share

The consent forms stated that the confidentiality of the information would be protected and that it would be used only for the evaluation of the data in this study without identifying information.

Locations