NCT07316244

Brief Summary

The aim of the study is to explore the epidemiology, including risk factors, causative microorganisms, complications and clinical outcomes of microbial keratitis among patients attending cornea clinic at Assiut University Hospital.

Trial Health

65
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
10mo left

Started Jan 2026

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress30%
Jan 2026Mar 2027

First Submitted

Initial submission to the registry

December 16, 2025

Completed
16 days until next milestone

Study Start

First participant enrolled

January 1, 2026

Completed
4 days until next milestone

First Posted

Study publicly available on registry

January 5, 2026

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2026

Expected
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2027

Last Updated

January 5, 2026

Status Verified

December 1, 2025

Enrollment Period

11 months

First QC Date

December 16, 2025

Last Update Submit

December 30, 2025

Conditions

KeratitisMicrobial Keratitis

Keywords

Mk

Outcome Measures

Primary Outcomes (1)

  • pattern of microbial keratitis in Assiut university hospital.

    Identification of different causative microbial agents of microbial keratitis among patients presenting to Assiut University Hospital.

    At initial presentation ( baseline)

Interventions

corneal scraping including direct smear, culture and sensitivityDIAGNOSTIC_TEST

corneal scraping including direct smear, culture and sensitivity

Eligibility Criteria

Sexall
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

1. Full history taking: age, gender, residency ( urbn or rural ), literacy, present or past medical and surgical histories 2. Full ophthalmological examination,visual acuity at presentation and after healing. 3. Slit-lamp biomicroscopy 3\. outcome of corneal scraping including direct smear, culture and sensitivity

You may qualify if:

  • All cases presented with Microbial keratitis at cornea clinic , Assiut university hospital during the study period.

You may not qualify if:

  • Non-microbial keratitis including Moorens ulcers, chemical burns, and Shield ulcers.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Keratitis

Interventions

Sensitivity and Specificity

Condition Hierarchy (Ancestors)

Corneal DiseasesEye Diseases

Intervention Hierarchy (Ancestors)

Epidemiologic Research DesignEpidemiologic MethodsInvestigative TechniquesStatistics as TopicMathematical ConceptsHealth Care Evaluation MechanismsQuality of Health CareHealth Care Quality, Access, and EvaluationPublic HealthEnvironment and Public Health

Central Study Contacts

Liza Mamdouh Mamdouh

CONTACT

01099972360liza.wissa@gmail.com

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Ophthalmology Resident doctor

Study Record Dates

First Submitted

December 16, 2025

First Posted

January 5, 2026

Study Start

January 1, 2026

Primary Completion (Estimated)

December 1, 2026

Study Completion (Estimated)

March 1, 2027

Last Updated

January 5, 2026

Record last verified: 2025-12