Pediatric Midline Post Fossa Tumors Prognostic Factors and Outcomes

NCT07315230 | Not Yet Recruiting

• 1 other identifier: Midline posterior fossa tumors
• Study Type: observational
• Target: 30
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study will follow children younger than 18 years with midline posterior fossa brain tumors who undergo standard surgical resection at Assiut University Hospital. The aim is to evaluate functional outcome using the modified Rankin Scale and to explore how tumor type, extent of resection, and perioperative factors are associated with postoperative morbidity and survival. Results may help improve risk stratification and guide individualized treatment strategies for pediatric patients with these tumors.

Conditions

Pediatric Tumor; Midline Posterior Fossa Tumors

Keywords

Pediatric; Midline Posterior Fossa Tumors; Prognostic factors

Outcome Measures

Primary Outcomes (1)

• Functional Outcome After Surgical Resection of Pediatric Midline Posterior Fossa Tumors

  Assessment of the patient's functional status using the modified Rankin Scale (mRS) after surgical resection of a midline posterior fossa tumor in children, categorized as good outcome (mRS 1-3) or poor outcome (mRS 4-6).

  6 months after surgery.

Eligibility Criteria

• Age: 0 Years - 17 Years
• Sex: all
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

Pediatric patients younger than 18 years presenting to the Neurosurgery Department, Assiut University Hospital, with radiologically confirmed midline posterior fossa brain tumors and considered candidates for surgical resection. Participants are recruited consecutively from routine clinical care and followed postoperatively for functional and radiological outcomes.

You may qualify if:

• patients less than 18 years old
• patient with midline posterior fossa tumors
• patient is fit for surgery

You may not qualify if:

• patinent older than 18 years old
• patients with non-midline posterior fossa or other brain tumors.
• patient is unfit for surgery .
• Incomplete Data: Missing essential study data.
• Secondary Malignancy: Metastatic disease.

Sponsors & Collaborators

• Assiut University: lead

MeSH Terms

Conditions

Neoplasms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident at Neurosurgery Department, Assiut University

Study Record Dates

• First Submitted: December 18, 2025
• First Posted: January 2, 2026
• Study Start: January 1, 2026
• Primary Completion (Estimated): January 1, 2027
• Study Completion (Estimated): February 1, 2027
• Last Updated: January 2, 2026

Record last verified: 2025-12