Primary Dysmenorrhea and Mobilization.

NCT07314021 | Completed

• 1 other identifier: E-10840098-202.3.02-4605
• Study Type: interventional
• Target: 72
• Locations: 1 country
• Sites: 1

Brief Summary

72 women diagnosed with primary dysmenorrhea were included in the study and divided into four groups. the first group received treatment with a mobilization approach, the second group received motor imagery-focused exercises and the third group, as a electrotherapy group and fourth received no treatment was applied.

Conditions

Primary Dysmenorrhea

Keywords

mobilization; primary dysmenorrhea; exercise

Outcome Measures

Primary Outcomes (1)

• Short-Form McGill Pain Questionnaire Total Pain Score

  Pain intensity was assessed using the Short-Form McGill Pain Questionnaire (SF-MPQ). The SF-MPQ total pain score, calculated as the sum of sensory and affective pain descriptor scores, was defined as the primary outcome. Higher scores indicate greater pain severity.

  12 weeks

Secondary Outcomes (4)

• Menstrual Attitude Questionnaire

  12 weeks

• Functional and Emotional Dysmenorrhea Scale

  12 weeks

• Menstrual Symptom Questionnaire

  12 weeks

• The Menstrual Distress Questionnaire

  12 weeks

Study Arms (4)

FEMOB

ACTIVE COMPARATOR

Structured multimodal mobilization (FEMOB) is a manual therapy-based mobilization protocol consisting of temporomandibular, occipitosacral, and sacroiliac joint mobilizations, abdominal myofascial release, and kinesio taping.

Other: FEMOB

MOPEXE

ACTIVE COMPARATOR

Participants in the MOPEXE arm receive a 60-minute Pilates-based motor imagery-focused pelvic floor exercise program twice weekly for 12 weeks. Each session consists of 5 minutes of meditation, 10 minutes of progressive relaxation training using the Bernstein-Borkovec method, 5 minutes of diaphragmatic and pursed-lip breathing exercises, 35 minutes of motor imagery-focused pelvic floor exercises, and a final 5 minutes of meditation. Outcomes are assessed at baseline and after completion of the 12-week intervention period.

Other: MOPEXE

Conventional treatment group

OTHER

The conventional treatment arm receives TENS and hot pack application. TENS is administered with the Chattanooga Intelect Advanced Combo system at 100 Hz and 200 µs for 30 minutes using two channels and four electrodes placed over the lumbar and suprapubic regions. Hot pack application is applied to the lumbar and suprapubic regions for a total of 20 minutes.

Other: Conventional Treatment group

CONTROL

NO INTERVENTION

Participants in the control group received no active treatment, exercise program, or physiotherapy intervention during the study period. They were instructed to continue their routine daily activities and not to initiate any new pharmacological or non-pharmacological treatment for dysmenorrhea symptoms during the study.

Interventions

FEMOB OTHER

FEMOB is a structured multimodal mobilization protocol consisting of temporomandibular, occipitosacral, and sacroiliac joint mobilizations, abdominal myofascial release, and kinesio taping.

FEMOB

MOPEXE OTHER

MOPEXE is a Pilates-based motor imagery-focused pelvic floor exercise program. Each 60-minute session consists of 5 minutes of meditation, 10 minutes of progressive relaxation training using the Bernstein-Borkovec method, 5 minutes of diaphragmatic and pursed-lip breathing exercises, 35 minutes of motor imagery-focused pelvic floor exercises, and a final 5 minutes of meditation. Sessions are delivered twice weekly for 12 weeks.

MOPEXE

Conventional Treatment group OTHER

The conventional treatment arm receives TENS and hot pack application. TENS is administered with the Chattanooga Intelect Advanced Combo system at 100 Hz and 200 µs for 30 minutes using two channels and four electrodes placed over the lumbar and suprapubic regions. Hot pack application is applied to the lumbar and suprapubic regions for 20 minutes.

Conventional treatment group

Eligibility Criteria

• Age: 18 Years - 30 Years
• Gender Eligibility Details: women
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Women aged 18-30 years
• Clinically confirmed primary dysmenorrhea
• Regular menstrual cycles during the previous six months
• Menstrual pain intensity of ≥4 cm on the Visual Analog Scale (VAS)
• Voluntary agreement to participate in the study

You may not qualify if:

• Secondary dysmenorrhea or gynecological pathology such as endometriosis, uterine fibroids, or pelvic inflammatory disease
• Pregnancy
• Pelvic physiotherapy within the previous six months
• Neurological, rheumatological, or serious systemic disease
• Communication difficulties preventing participation or questionnaire completion
• Regular use of oral contraceptives

Sponsors & Collaborators

• Medipol University: lead

Study Sites (1)

Medipol University

Istanbul, 34000, Turkey (Türkiye)

Location

Related Publications (1)

• Toprak Celenay S, Kavalci B, Karakus A, Alkan A. Effects of kinesio tape application on pain, anxiety, and menstrual complaints in women with primary dysmenorrhea: A randomized sham-controlled trial. Complement Ther Clin Pract. 2020 May;39:101148. doi: 10.1016/j.ctcp.2020.101148. Epub 2020 Mar 18.

  PMID: 32379680 BACKGROUND

Related Links

• Related Info
• Related Info

MeSH Terms

Conditions

Motor Activity

Condition Hierarchy (Ancestors)

Behavior

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: physiotherapist

Study Record Dates

• First Submitted: December 4, 2025
• First Posted: January 2, 2026
• Study Start: December 5, 2025
• Primary Completion: June 1, 2026
• Study Completion: June 1, 2026
• Last Updated: July 1, 2026

Record last verified: 2026-06

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, SAP, ICF, CSR, ANALYTIC CODE

Locations

TU (1)