Antiplatelet Use in Dementia Subtypes

NCT07313137 | Completed

• 1 other identifier: GTRH-ANTIPL-DEM-01
• Study Type: observational
• Target: 683
• Locations: 0 countries
• Sites: N/A

Brief Summary

This population-based retrospective cohort study aimed to evaluate the appropriateness of antiplatelet therapy use among older adults with all-cause dementia and across different dementia subtypes. Medical records of patients aged 65 years and older who were evaluated at a tertiary-level geriatric outpatient clinic were reviewed. Dementia subtypes were classified according to internationally accepted diagnostic criteria. Patterns of antiplatelet use were assessed in accordance with current guideline recommendations. The study sought to determine the appropriateness of antiplatelet use across dementia subtypes and to describe real-world prescribing practices in this population.

Conditions

Dementia; Dementia Disorder

Keywords

Antiplatelet therapy; Older adults; Dementia subtypes

Outcome Measures

Primary Outcomes (1)

• Appropriateness of antiplatelet therapy use

  Assessment of the appropriateness of antiplatelet therapy use according to current guideline recommendations among older adults with dementia.

  At baseline (first geriatric outpatient clinic visit)

Study Arms (1)

Dementia cohort

This cohort includes older adults aged 65 years and older diagnosed with dementia who were evaluated in a tertiary geriatric outpatient clinic. No intervention was assigned, as this is a retrospective observational study.

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study population consists of older adults aged 65 years and older with a diagnosis of dementia who were evaluated in a tertiary-level geriatric outpatient clinic.

You may qualify if:

• Age 65 years and older.
• Diagnosis of dementia based on internationally accepted diagnostic criteria.
• Evaluation at a tertiary-level geriatric outpatient clinic.

You may not qualify if:

• Patients with incomplete or inaccessible medical records.
• Individuals with missing data on antiplatelet therapy use.

Sponsors & Collaborators

• Gulhane Training and Research Hospital: lead

MeSH Terms

Conditions

Dementia; Alzheimer Disease

Condition Hierarchy (Ancestors)

Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Neurocognitive Disorders; Mental Disorders; Tauopathies; Neurodegenerative Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: MD, Geriatrics Fellow

Study Record Dates

• First Submitted: December 17, 2025
• First Posted: December 31, 2025
• Study Start: December 1, 2016
• Primary Completion: March 1, 2025
• Study Completion: March 1, 2025
• Last Updated: December 31, 2025

Record last verified: 2025-12

Data Sharing

• IPD Sharing: Will not share