NCT07312994

Brief Summary

This observational study aims to investigate the impact of different dietary patterns on brain tissue biomarkers in healthy young adults by measuring blood levels of NfL and GFAP. The primary research question is: Do vegan, vegetarian, or omnivorous diets influence NfL and GFAP levels?

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
300

participants targeted

Target at P75+ for all trials

Timeline
4mo left

Started Dec 2025

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress55%
Dec 2025Sep 2026

First Submitted

Initial submission to the registry

December 9, 2025

Completed
9 days until next milestone

Study Start

First participant enrolled

December 18, 2025

Completed
13 days until next milestone

First Posted

Study publicly available on registry

December 31, 2025

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2026

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2026

Expected
Last Updated

December 31, 2025

Status Verified

December 1, 2025

Enrollment Period

3 months

First QC Date

December 9, 2025

Last Update Submit

December 17, 2025

Conditions

Neurofilament Light ChainGlial Fibrillary Acidic ProteinGFAPVegan DietVegetarian Diet

Outcome Measures

Primary Outcomes (1)

  • Blood levels of the following biomarkers: neurofilament light chain (NfL) in pg/mL, glial fibrillary acidic protein (GFAP) in pg/mL.

    Once at baseline

Study Arms (3)

Omnivore

Vegan

Vegetarian

Eligibility Criteria

Age18 Years - 40 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

Young and healthy individuals aged between 18 and 40 years

You may qualify if:

  • Healthy individuals who have followed a vegan, vegetarian, or omnivorous diet for at least one consecutive year
  • Aged between 18 and 40 years
  • Provision of written informed consent

You may not qualify if:

  • Diagnose neurological disorders (e.g. neurodegenerative, inflammatory, autoimmune, infectious, vascular)
  • Eating disorders
  • Excessive alcohol consumption
  • Pregnancy
  • Recent moderate to severe infection (within the past 12 weeks) , including SARS-CoV-2
  • Recent trauma, injury, or surgery (within the past 12 weeks)
  • Significant BMI fluctuations (\>5 points) within the last year
  • Patients who have been using Proton pump inhibitors (PPIs) for an extended period (e.g., 1 month).

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Christian-Doppler-Klinik

Salzburg, Salzburg, 5020, Austria

RECRUITING

Biospecimen

Retention: SAMPLES WITHOUT DNA

Blood biomarkers

MeSH Terms

Conditions

Charcot-Marie-Tooth disease, Type 1F

Central Study Contacts

Tobias Moser, Prof.

CONTACT

+435725534720t.moser@salk.at

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
apl. Prof.

Study Record Dates

First Submitted

December 9, 2025

First Posted

December 31, 2025

Study Start

December 18, 2025

Primary Completion

April 1, 2026

Study Completion (Estimated)

September 1, 2026

Last Updated

December 31, 2025

Record last verified: 2025-12

Data Sharing

IPD Sharing
Will not share

Locations

AU(1)