Evaluation of Postoperative Pain and Success Rate Between Lateral Condensation and Warm Vertical Obturation Techniques

NCT07310212 | Recruiting DMC

• 1 other identifier: 224000393
• Study Type: interventional
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

Brief Summary Postoperative pain is a common complication following root canal treatment, particularly in necrotic teeth with asymptomatic apical periodontitis. Although obturation technique has been suggested as a contributing factor to postoperative discomfort, direct clinical comparisons between commonly used methods remain limited. Cold lateral condensation has traditionally been considered the standard obturation technique, while warm vertical obturation systems such as Obtura II have gained popularity due to their potential for improved adaptation of gutta-percha. This randomized controlled clinical trial aims to compare postoperative pain experience and treatment outcomes following cold lateral condensation and warm vertical obturation in single-rooted necrotic teeth. Postoperative pain will be assessed during the early healing period, along with patient-reported outcomes and short-term clinical and radiographic healing. The results of this study are expected to provide clinically relevant evidence to support evidence-based obturation technique selection and improve patient comfort in endodontic practice.

Conditions

Necrotic Pulp; Asymptomatic Apical Periodontitis

Outcome Measures

Primary Outcomes (1)

• Postoperative pain intensity following two different obturation techniques

  Visual Analog Scale (VAS), 0-10 0 represents no pain, 10 represents excruciating pain

  Baseline (6 hours post-treatment), 12 hours post-treatment,1 day, 2 days, 3 days, 4 days, and daily up to 7 days post-treatment

Secondary Outcomes (3)

• Patient Satisfaction

  Immediately after treatment6 months post treatment

• Assess the need for pain medication

  6 hours post treatment12 hours post treatment1 day2 days3 days4 days up to the complete resolution of pain

• Evaluation of diffrence in success rate

  Immediately After treatment 6 months posttreatment

Study Arms (2)

Warm vertical obturation

ACTIVE COMPARATOR

Procedure: Warm Vertical Condensation (WVO)

Cold lateral condensation obturation

EXPERIMENTAL

Procedure: Cold Lateral Condensation (CLC)

Interventions

Warm Vertical Condensation (WVO) PROCEDURE

Following standard endodontic cleaning and shaping with rotary instrumentation and irrigation, canals will be obturated using the warm vertical condensation technique. After placement of a master cone coated with AH Plus sealer, heat is applied to soften and vertically compact the gutta-percha within the canal. The Obtura II system will be used to backfill the canal with thermoplasticized gutta-percha, ensuring three-dimensional adaptation and dense filling of the root canal space.

Warm vertical obturation

Cold Lateral Condensation (CLC) PROCEDURE

Following standard endodontic cleaning and shaping with rotary instrumentation and irrigation, canals will be obturated using the cold lateral condensation technique. A master gutta-percha cone coated with sealer (AH Plus) will be inserted, and accessory cones will be compacted laterally using spreaders until the canal is fully obturated. This technique is widely regarded as the traditional standard method for root canal obturation.

Cold lateral condensation obturation

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adults aged 18 years or older.
• Patients requiring endodontic treatment for single-rooted necrotic teeth.
• Radiographic and clinical diagnosis of asymptomatic apical periodontitis.
• Ability to understand the study and provide written informed consent.

You may not qualify if:

• Teeth diagnosed with symptomatic apical periodontitis.
• Pregnant or lactating women.
• Patients with systemic diseases affecting pain perception (e.g., uncontrolled diabetes, chronic pain conditions).
• Teeth that have been previously endodontically treated.
• Patients taking medications that may influence pain perception (e.g., chronic analgesic or anti-inflammatory drug use).
• Periodontally compromised teeth with significant bone loss or mobility.

Sponsors & Collaborators

• University of Jordan: lead

Study Sites (1)

University of Jordan Hospital

Amman, Amman Governate, 11942, Jordan

RECRUITING

MeSH Terms

Conditions

Dental Pulp Necrosis

Condition Hierarchy (Ancestors)

Dental Pulp Diseases; Tooth Diseases; Stomatognathic Diseases; Necrosis; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Central Study Contacts

Dalin Jihad AlSawaftah, Endodontic resident, DDs

CONTACT

+962779420787; dalin7495@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Endodontic resident

Study Record Dates

• First Submitted: August 29, 2025
• First Posted: December 30, 2025
• Study Start: October 17, 2024
• Primary Completion (Estimated): June 1, 2026
• Study Completion (Estimated): December 1, 2026
• Last Updated: April 2, 2026

Record last verified: 2026-03

Locations

JO (1)