Biomarker Feedback Intervention
An Examination of the Feasibility of a Brief Personalized Alcohol Biomarker Feedback Intervention for High-risk College Students
1 other identifier
interventional
150
1 country
1
Brief Summary
The goal of the study is to examine alcohol use behaviors of young adults through the use of testing the feasibility of adding an innovative brief personalized alcohol biomarker feedback component (TAC feedback) to an existing efficacious personalized feedback intervention, eCHECKUP TO GO (eCTG), and how (if at all) the intervention impacts drinking behaviors in high-risk college students. The study will conduct a feasibility assessment of the TAC feedback component, and will also assess the effects of the eCTG + TAC at 6-months post-baseline relative to an eCTG only group.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Mar 2026
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
December 15, 2025
CompletedFirst Posted
Study publicly available on registry
December 29, 2025
CompletedStudy Start
First participant enrolled
March 15, 2026
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 15, 2027
ExpectedStudy Completion
Last participant's last visit for all outcomes
May 15, 2027
December 29, 2025
December 1, 2025
1.2 years
December 15, 2025
December 15, 2025
Conditions
Keywords
Outcome Measures
Primary Outcomes (3)
Examine changes in Transdermal Alcohol Concentration (TAC) rise rate
TAC rise rate will be collected via the BACtrack Skyn wrist sensor, which measures transdermal alcohol concentration (TAC) in micrograms of ethanol per liter of air every 20 seconds to obtain biomarkers - rise rate is a TAC increase.
Baseline, 6 months
Examine changes in Transdermal Alcohol Concentration (TAC) peak intoxication level
TAC peak will be collected via the BACtrack Skyn wrist sensor, which measures transdermal alcohol concentration (TAC) in micrograms of ethanol per liter of air every 20 seconds to obtain biomarkers - peak is the maximum TAC recorded per day.
Baseline, 6 months
Examine high risk drinking days
Heavy episodic drinking (HED) days are recorded when women indicate drinking 4+ drinks in 2 hour window/men indicate drinking 5+ drinks in 2 hour window. High-intensity drinking (HID) days are recorded when women indicate drinking 8+ drinks in 2 hour window/men indicate drinking 10+ drinks in 2 hour window.
Baseline, 6 months
Secondary Outcomes (2)
Examine negative consequences of alcohol use
Baseline, 6 months
Examine Alcohol Use Disorder (AUD) symptoms
Baseline, 6 months
Study Arms (2)
eCHECKUP TO GO (eCTG)
EXPERIMENTALA brief, web-based program designed by San Diego State University to reduce high-risk drinking by providing personalized normative feedback regarding alcohol use, risk factors, and risks associated with drinking and accurate information about alcohol
eCHECKUPTOGO + brief personalized biomarker feedback intervention (eCTG + TAC)
EXPERIMENTALParticipants will receive the eCHECKUPTOGO in addition to the transdermal alcohol concentration (TAC) personalized feedback. The TAC is a brief individually delivered intervention based on the principles of Motivational Interviewing and focuses on increasing students' motivation to reduce harmful drinking by drinking in a safer, less risky manner. Participants will receive information on their drinking (both from the TAC sensor and daily diary data). Participants will be asked about drinking events during the past 2 weeks (how reflective they were of typical patterns and if a night stood out as particularly negative). Students will receive information and visual representations about TAC rise rates and peaks, and then be shown how their drinking during the past 2 weeks maps onto those visuals.
Interventions
A brief, web-based program designed by San Diego State University to reduce high-risk drinking by providing personalized normative feedback regarding alcohol use, risk factors, and risks associated with drinking and accurate information about alcohol
Participants will receive the eCHECKUPTOGO in addition to the transdermal alcohol concentration (TAC) personalized feedback. The TAC is a brief individually delivered intervention based on the principles of Motivational Interviewing and focuses on increasing students' motivation to reduce harmful drinking by drinking in a safer, less risky manner. Participants will receive information on their drinking (both from the TAC sensor and daily diary data). Participants will be asked about drinking events during the past 2 weeks (how reflective they were of typical patterns and if a night stood out as particularly negative). Students will receive information and visual representations about TAC rise rates and peaks, and then be shown how their drinking during the past 2 weeks maps onto those visuals.
Eligibility Criteria
You may qualify if:
- Between the ages of 18-23 at enrollment
- Endorse drinking 4+/5+ (women/men) on a typical Friday or Saturday in the past 3-months
- Report at least 1 alcohol-induced blackout in the past 3-months
- Willing to wear a TAC sensor for 14 days at Waves 1 and 2
You may not qualify if:
- Younger than 18 at baseline
- Not fluent in English
- No Internet access
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
The Pennsylvania State University
University Park, Pennsylvania, 16802, United States
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Kimberly Mallett, PhD
The Pennsylvania State University
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- INVESTIGATOR
- Purpose
- PREVENTION
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Research Professor
Study Record Dates
First Submitted
December 15, 2025
First Posted
December 29, 2025
Study Start
March 15, 2026
Primary Completion (Estimated)
May 15, 2027
Study Completion (Estimated)
May 15, 2027
Last Updated
December 29, 2025
Record last verified: 2025-12
Data Sharing
- IPD Sharing
- Will share
- Access Criteria
- Individuals will request access to the data via a data access request through the data archive.
As part of funding requirements, data collected will be submitted to the NIAAA Data Archive.