Microdochectomy for Chronic Non Dilated Single Duct Nipple Discharge

NCT07305558 | Active Not Recruiting DMC

• 1 other identifier: 1248\27-4-2025
• Study Type: interventional
• Target: 15
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this clinical trial is to evaluate the efficacy of a new technique in treatment of single milk duct discharge. The main questions it aims to answer are: Does ultrasound guided microdochectomy is feasible in non dilated milk duct? What are the surgical outcomes of this technique? Participants will: Had ultrasound microdochectomy After discharge, patients will visit the clinic twice every week for two weeks, a visit or call after 3 month

Conditions

Nipple Discharge

Keywords

nipple discharge; microdochectomy; breast

Outcome Measures

Primary Outcomes (1)

• Nipple discharge

  stop of spontaneous and induced nipple discharge by absence of stain on dressing and clothes and by squeezing the nipple

  from first day after surgery to 3 months after surgery

Secondary Outcomes (5)

• operation time

  from skin incision to closure

• Bleeding

  from skin incision to skin closure

• post operative pain

  from the day of surgery to one week after surgery

• hospital stay

  from the first day of surgery to 3 days after surgery

• wound infection

  from one day to 2 weeks after surgery

Study Arms (1)

patients with single milk duct discharge

EXPERIMENTAL

Procedure: ultrasound guided microdochectomy

Interventions

ultrasound guided microdochectomy PROCEDURE

ultrasound was used to perform microdochectomy for single not dilated milk duct without cannulation

patients with single milk duct discharge

Eligibility Criteria

• Age: 18 Years+
• Gender Eligibility Details: this problem is evident only in female breast
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• females above 18 years old with single not dilated milk duct discharge after failure of medical treatment

You may not qualify if:

• breast cancer
• patients with multiple or dilated milk duct discharge.
• contraindications to surgery or ‬anaesthesia
• patient above 18 years old
• patients refuse to participate in the study

Sponsors & Collaborators

• Zagazig University: lead

Study Sites (1)

faculty of medicine, Zagazig University

Zagazig, Zagazig, 44519, Egypt

Location

MeSH Terms

Conditions

Galactorrhea

Condition Hierarchy (Ancestors)

Lactation Disorders; Puerperal Disorders; Pregnancy Complications; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Breast Diseases; Skin Diseases; Skin and Connective Tissue Diseases

Study Officials

• Reham Zakaria, M.D

  faculty of medicine, Zagazig University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: lecturer of general surgery

Study Record Dates

• First Submitted: December 12, 2025
• First Posted: December 26, 2025
• Study Start: April 27, 2025
• Primary Completion: April 27, 2026
• Study Completion: April 27, 2026
• Last Updated: December 26, 2025

Record last verified: 2025-12

Locations

EG (1)