Emotional Processes in Adults With Intellectual Developmental Disorder

NCT07303270 | Recruiting

• 1 other identifier: 2025-A01946-43
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

Emotions play a crucial part in the quality of life, interpersonal relationships and mental health in general. In adults presenting with intellectual developmental disorder (IDD), emotional abilities may be hindered, thus leading to more challenging behaviors. A better understanding of emotional processes of adults with IDD may help improve the efficiency of behavioral interventions and better improve their quality of life. The primary goal of this study is to better characterize the abilities and weaknesses of adults with IDD concerning their emotional processes, in comparison to a healthy population. The secondary goals are :

• to determine if these difficulties are underlined by oculomotor and attention (auditory and visual) processes
• to determine if behavioral difficulties, as reported by the families of adults with IDD, are underlined by specific difficulties in facial emotion recognition, emotion identification in context and/or identification of vocal emotions.

Conditions

Intellectual Developmental Disorder

Keywords

Intellectual Developmental Disorder; emotional processing; Cognitive assessments; Social cognition

Outcome Measures

Primary Outcomes (1)

• proportion of correct answers on the ACQUISS battery

  proportion of correct answers in each of the 3 tasks

  Baseline

Secondary Outcomes (7)

• Proportion of correct answers on the Entangled lines test

  Baseline

• Proportion of correct answers on the NSUCO test

  Baseline

• Proportion of correct answers on an auditory attentional task (NEPSY-II)

  Baseline

• Proportion of correct signs barred on the TeddyBear task

  Baseline

• Proportion of correct signs barred on the letter task

  Baseline

Study Arms (2)

IDD group

EXPERIMENTAL

adults with Intellectual Developmental Disorder

Other: ACQUISS protocol assessing emotional processing.

Control group

OTHER

healthy adults

Other: ACQUISS protocol assessing emotional processing.

Interventions

ACQUISS protocol assessing emotional processing. OTHER

Task 1: 5 minute facial emotion recognition test to identify isolated facial expressions. 6 drawn faces, without gender bias, without hair, expressing the 6 universal emotions will be presented. The emotions are: happiness, sadness, anger, fear, surprise and disgust. Task 2 : identifying a character's emotion in a social context (20 min). The subject is presented with drawn social contexts, one character is always in orange, and the face is left blank. The subject then has to choose amongst 6 emotions (happiness, sadness, anger, fear, surprise and disgust) which one would correspond the most to the emotion expressed by the character in orange. Task 3 : recognizing vocal emotions (15 min). The subject is presented with dialogues of 3 sentences. The 3 sentences are expressed with a vocal emotion (same emotion for the 3 sentences). The contents of the sentences are neutral At the end of each dialogue, the subject has to show which emotion was expressed.

Control group; IDD group

Eligibility Criteria

• Age: 18 Years - 35 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• IDD group :
• Diagnosis of IDD according to DSM-V criteria
• aged between 18 and 3 years
• French speaking
• Membership or entitlement to a social security plan
• informed consent, or that of the tutor, to take part in the study
• presence of a caregiver to complete the questionnaires at V2.
• Control group :
• aged between 18 and 35 years
• French speaking
• Membership or entitlement to a social security plan
• Informed written consent to take part in the study.

You may not qualify if:

• IDD group :
• visual or auditory impairments, evaluated at V1
• non stabilized epilepsy
• undergoing treatments that can impact brain or psychological functioning
• major motor disorders
• breastfeeding or pregnant woman
• Control group :
• neurodevelopmental or psychiatric disorder
• history of brain trauma (TBI, stroke, etc…) or non-stabilized epilepsy
• visual or auditory impairments, evaluated at V1
• non stabilized epilepsy
• undergoing treatments that can impact brain or psychological functioning
• major motor disorders
• breastfeeding or pregnant woman

Sponsors & Collaborators

• Hôpital le Vinatier: lead

Study Sites (1)

CH Le Vinatier

Bron, 69500, France

RECRUITING

MeSH Terms

Conditions

Intellectual Disability

Condition Hierarchy (Ancestors)

Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Neurodevelopmental Disorders; Mental Disorders

Central Study Contacts

Marie-Noelle Babinet, PhD

CONTACT

+33437915380; marie-noelle.babinet@ch-le-vinatier.fr

Méline Devaluez, PhD

CONTACT

+33437915514; meline.devaluez@ch-le-vinatier.fr

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: IDD group compared to control group

Study Record Dates

• First Submitted: December 11, 2025
• First Posted: December 24, 2025
• Study Start: February 19, 2026
• Primary Completion (Estimated): August 1, 2028
• Study Completion (Estimated): November 20, 2028
• Last Updated: April 1, 2026

Record last verified: 2026-03

Locations

FR (1)